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Oncology exploration: charting cancer medicinal chemistry space.
Lloyd DG, Golfis G, Knox AJ, Fayne D, Meegan MJ, Oprea TI. Lloyd DG, et al. Among authors: fayne d. Drug Discov Today. 2006 Feb;11(3-4):149-59. doi: 10.1016/S1359-6446(05)03688-3. Drug Discov Today. 2006. PMID: 16533713 Review.
The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gagliardi M, McElligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, Lawler M, Meegan MJ, Zisterer DM. Greene LM, et al. Among authors: fayne d. J Pharmacol Exp Ther. 2010 Nov;335(2):302-13. doi: 10.1124/jpet.110.170415. Epub 2010 Aug 10. J Pharmacol Exp Ther. 2010. PMID: 20699436
49 results