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The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy.
Vázquez-Fernández E, Vos MR, Afanasyev P, Cebey L, Sevillano AM, Vidal E, Rosa I, Renault L, Ramos A, Peters PJ, Fernández JJ, van Heel M, Young HS, Requena JR, Wille H. Vázquez-Fernández E, et al. Among authors: requena jr. PLoS Pathog. 2016 Sep 8;12(9):e1005835. doi: 10.1371/journal.ppat.1005835. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27606840 Free PMC article.
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.
Stincardini C, Massignan T, Biggi S, Elezgarai SR, Sangiovanni V, Vanni I, Pancher M, Adami V, Moreno J, Stravalaci M, Maietta G, Gobbi M, Negro A, Requena JR, Castilla J, Nonno R, Biasini E. Stincardini C, et al. Among authors: requena jr. PLoS One. 2017 Aug 7;12(8):e0182589. doi: 10.1371/journal.pone.0182589. eCollection 2017. PLoS One. 2017. PMID: 28787011 Free PMC article.
Cofactors influence the biological properties of infectious recombinant prions.
Fernández-Borges N, Di Bari MA, Eraña H, Sánchez-Martín M, Pirisinu L, Parra B, Elezgarai SR, Vanni I, López-Moreno R, Vaccari G, Venegas V, Charco JM, Gil D, Harrathi C, D'Agostino C, Agrimi U, Mayoral T, Requena JR, Nonno R, Castilla J. Fernández-Borges N, et al. Among authors: requena jr. Acta Neuropathol. 2018 Feb;135(2):179-199. doi: 10.1007/s00401-017-1782-y. Epub 2017 Nov 1. Acta Neuropathol. 2018. PMID: 29094186
The prion 2018 round tables (I): the structure of PrPSc.
Baskakov IV, Caughey B, Requena JR, Sevillano AM, Surewicz WK, Wille H. Baskakov IV, et al. Among authors: requena jr. Prion. 2019 Jan;13(1):46-52. doi: 10.1080/19336896.2019.1569450. Prion. 2019. PMID: 30646817 Free PMC article.
Ok Google, how could I design therapeutics against prion diseases?
Rigoli M, Spagnolli G, Faccioli P, Requena JR, Biasini E. Rigoli M, et al. Among authors: requena jr. Curr Opin Pharmacol. 2019 Feb;44:39-45. doi: 10.1016/j.coph.2019.03.015. Epub 2019 May 3. Curr Opin Pharmacol. 2019. PMID: 31059982 Review.
91 results