Houghton AN - Search Results

1

Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.

Budhu S, Schaer DA, Li Y, Toledo-Crow R, Panageas K, Yang X, Zhong H, Houghton AN, Silverstein SC, Merghoub T, Wolchok JD. Budhu S, et al. Among authors: houghton an. Sci Signal. 2017 Aug 29;10(494):eaak9702. doi: 10.1126/scisignal.aak9702. Sci Signal. 2017. PMID: 28851824 Free PMC article.

2

Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation.

Cohen AD, Schaer DA, Liu C, Li Y, Hirschhorn-Cymmerman D, Kim SC, Diab A, Rizzuto G, Duan F, Perales MA, Merghoub T, Houghton AN, Wolchok JD. Cohen AD, et al. Among authors: houghton an. PLoS One. 2010 May 3;5(5):e10436. doi: 10.1371/journal.pone.0010436. PLoS One. 2010. PMID: 20454651 Free PMC article.

3

GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability.

Schaer DA, Budhu S, Liu C, Bryson C, Malandro N, Cohen A, Zhong H, Yang X, Houghton AN, Merghoub T, Wolchok JD. Schaer DA, et al. Among authors: houghton an. Cancer Immunol Res. 2013 Nov;1(5):320-31. doi: 10.1158/2326-6066.CIR-13-0086. Cancer Immunol Res. 2013. PMID: 24416730 Free PMC article.

4

Immunity to melanoma: unraveling the relation of tumor immunity and autoimmunity.

Ramirez-Montagut T, Turk MJ, Wolchok JD, Guevara-Patino JA, Houghton AN. Ramirez-Montagut T, et al. Among authors: houghton an. Oncogene. 2003 May 19;22(20):3180-7. doi: 10.1038/sj.onc.1206462. Oncogene. 2003. PMID: 12789294 Review.

5

Optimization of a self antigen for presentation of multiple epitopes in cancer immunity.

Guevara-Patiño JA, Engelhorn ME, Turk MJ, Liu C, Duan F, Rizzuto G, Cohen AD, Merghoub T, Wolchok JD, Houghton AN. Guevara-Patiño JA, et al. Among authors: houghton an. J Clin Invest. 2006 May;116(5):1382-90. doi: 10.1172/JCI25591. Epub 2006 Apr 13. J Clin Invest. 2006. PMID: 16614758 Free PMC article.

6

Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity.

Cohen AD, Diab A, Perales MA, Wolchok JD, Rizzuto G, Merghoub T, Huggins D, Liu C, Turk MJ, Restifo NP, Sakaguchi S, Houghton AN. Cohen AD, et al. Among authors: houghton an. Cancer Res. 2006 May 1;66(9):4904-12. doi: 10.1158/0008-5472.CAN-05-2813. Cancer Res. 2006. PMID: 16651447 Free PMC article.

7

Improved tumor immunity using anti-tyrosinase related protein-1 monoclonal antibody combined with DNA vaccines in murine melanoma.

Saenger YM, Li Y, Chiou KC, Chan B, Rizzuto G, Terzulli SL, Merghoub T, Houghton AN, Wolchok JD. Saenger YM, et al. Among authors: houghton an. Cancer Res. 2008 Dec 1;68(23):9884-91. doi: 10.1158/0008-5472.CAN-08-2233. Cancer Res. 2008. PMID: 19047169 Free PMC article.

8

Development of effective vaccines for old mice in a tumor model.

Posnett DN, Engelhorn ME, Lin Y, Merghoub T, Duan F, Wolchok JD, Houghton AN. Posnett DN, et al. Among authors: houghton an. Vaccine. 2009 Feb 11;27(7):1093-100. doi: 10.1016/j.vaccine.2008.11.112. Epub 2008 Dec 25. Vaccine. 2009. PMID: 19103244 Free PMC article.

9

Self-antigen-specific CD8+ T cell precursor frequency determines the quality of the antitumor immune response.

Rizzuto GA, Merghoub T, Hirschhorn-Cymerman D, Liu C, Lesokhin AM, Sahawneh D, Zhong H, Panageas KS, Perales MA, Altan-Bonnet G, Wolchok JD, Houghton AN. Rizzuto GA, et al. Among authors: houghton an. J Exp Med. 2009 Apr 13;206(4):849-66. doi: 10.1084/jem.20081382. Epub 2009 Mar 30. J Exp Med. 2009. PMID: 19332877 Free PMC article.

10

Immune rejection of mouse tumors expressing mutated self.

Duan F, Lin Y, Liu C, Engelhorn ME, Cohen AD, Curran M, Sakaguchi S, Merghoub T, Terzulli S, Wolchok JD, Houghton AN. Duan F, et al. Among authors: houghton an. Cancer Res. 2009 Apr 15;69(8):3545-53. doi: 10.1158/0008-5472.CAN-08-2779. Epub 2009 Apr 7. Cancer Res. 2009. PMID: 19351857 Free PMC article.

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