DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment.
Saunders R, Kaul H, Berair R, Gonem S, Singapuri A, Sutcliffe AJ, Chachi L, Biddle MS, Kaur D, Bourne M, Pavord ID, Wardlaw AJ, Siddiqui SH, Kay RA, Brook BS, Smallwood RH, Brightling CE.
Saunders R, et al. Among authors: kay ra.
Sci Transl Med. 2019 Feb 13;11(479):eaao6451. doi: 10.1126/scitranslmed.aao6451.
Sci Transl Med. 2019.
PMID: 30760581
Free article.
Clinical Trial.