Hughson AG - Search Results

1

Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants.

Caughey B, Orru CD, Groveman BR, Hughson AG, Manca M, Raymond LD, Raymond GJ, Race B, Saijo E, Kraus A. Caughey B, et al. Among authors: hughson ag. Prog Mol Biol Transl Sci. 2017;150:375-388. doi: 10.1016/bs.pmbts.2017.06.003. Epub 2017 Jul 27. Prog Mol Biol Transl Sci. 2017. PMID: 28838670 Review.

2

The most infectious prion protein particles.

Silveira JR, Raymond GJ, Hughson AG, Race RE, Sim VL, Hayes SF, Caughey B. Silveira JR, et al. Among authors: hughson ag. Nature. 2005 Sep 8;437(7056):257-61. doi: 10.1038/nature03989. Nature. 2005. PMID: 16148934 Free PMC article.

3

Fractionation of prion protein aggregates by asymmetrical flow field-flow fractionation.

Silveira JR, Hughson AG, Caughey B. Silveira JR, et al. Among authors: hughson ag. Methods Enzymol. 2006;412:21-33. doi: 10.1016/S0076-6879(06)12002-9. Methods Enzymol. 2006. PMID: 17046649 Review.

4

Transmission and adaptation of chronic wasting disease to hamsters and transgenic mice: evidence for strains.

Raymond GJ, Raymond LD, Meade-White KD, Hughson AG, Favara C, Gardner D, Williams ES, Miller MW, Race RE, Caughey B. Raymond GJ, et al. Among authors: hughson ag. J Virol. 2007 Apr;81(8):4305-14. doi: 10.1128/JVI.02474-06. Epub 2007 Feb 7. J Virol. 2007. PMID: 17287284 Free PMC article.

5

Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein.

Atarashi R, Moore RA, Sim VL, Hughson AG, Dorward DW, Onwubiko HA, Priola SA, Caughey B. Atarashi R, et al. Among authors: hughson ag. Nat Methods. 2007 Aug;4(8):645-50. doi: 10.1038/nmeth1066. Epub 2007 Jul 22. Nat Methods. 2007. PMID: 17643109

6

Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking.

Atarashi R, Wilham JM, Christensen L, Hughson AG, Moore RA, Johnson LM, Onwubiko HA, Priola SA, Caughey B. Atarashi R, et al. Among authors: hughson ag. Nat Methods. 2008 Mar;5(3):211-2. doi: 10.1038/nmeth0308-211. Nat Methods. 2008. PMID: 18309304 No abstract available.

7

Human variant Creutzfeldt-Jakob disease and sheep scrapie PrP(res) detection using seeded conversion of recombinant prion protein.

Orrú CD, Wilham JM, Hughson AG, Raymond LD, McNally KL, Bossers A, Ligios C, Caughey B. Orrú CD, et al. Among authors: hughson ag. Protein Eng Des Sel. 2009 Aug;22(8):515-21. doi: 10.1093/protein/gzp031. Epub 2009 Jul 1. Protein Eng Des Sel. 2009. PMID: 19570812 Free PMC article.

8

Effect of glycans and the glycophosphatidylinositol anchor on strain dependent conformations of scrapie prion protein: improved purifications and infrared spectra.

Baron GS, Hughson AG, Raymond GJ, Offerdahl DK, Barton KA, Raymond LD, Dorward DW, Caughey B. Baron GS, et al. Among authors: hughson ag. Biochemistry. 2011 May 31;50(21):4479-90. doi: 10.1021/bi2003907. Epub 2011 May 3. Biochemistry. 2011. PMID: 21539311 Free PMC article.

9

Time course of prion seeding activity in cerebrospinal fluid of scrapie-infected hamsters after intratongue and intracerebral inoculations.

Orrù CD, Hughson AG, Race B, Raymond GJ, Caughey B. Orrù CD, et al. Among authors: hughson ag. J Clin Microbiol. 2012 Apr;50(4):1464-6. doi: 10.1128/JCM.06099-11. Epub 2012 Jan 11. J Clin Microbiol. 2012. PMID: 22238438 Free PMC article.

10

New generation QuIC assays for prion seeding activity.

Orrù CD, Wilham JM, Vascellari S, Hughson AG, Caughey B. Orrù CD, et al. Among authors: hughson ag. Prion. 2012 Apr-Jun;6(2):147-52. doi: 10.4161/pri.19430. Epub 2012 Apr 1. Prion. 2012. PMID: 22421206 Free PMC article. Review.

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