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HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies.
Bobrowicz M, Dwojak M, Pyrzynska B, Stachura J, Muchowicz A, Berthel E, Dalla-Venezia N, Kozikowski M, Siernicka M, Miazek N, Zapala P, Domagala A, Bojarczuk K, Malenda A, Barankiewicz J, Graczyk-Jarzynka A, Zagozdzon A, Gabrysiak M, Diaz JJ, Karp M, Lech-Maranda E, Firczuk M, Giannopoulos K, Efremov DG, Laurenti L, Baatout D, Frenzel L, Malinowska A, Slabicki M, Zenz T, Zerrouqi A, Golab J, Winiarska M. Bobrowicz M, et al. Among authors: muchowicz a. Blood. 2017 Oct 5;130(14):1628-1638. doi: 10.1182/blood-2016-08-736066. Epub 2017 Aug 22. Blood. 2017. PMID: 28830887 Free article.
Prenyltransferases regulate CD20 protein levels and influence anti-CD20 monoclonal antibody-mediated activation of complement-dependent cytotoxicity.
Winiarska M, Nowis D, Bil J, Glodkowska-Mrowka E, Muchowicz A, Wanczyk M, Bojarczuk K, Dwojak M, Firczuk M, Wilczek E, Wachowska M, Roszczenko K, Miaczynska M, Chlebowska J, Basak GW, Golab J. Winiarska M, et al. Among authors: muchowicz a. J Biol Chem. 2012 Sep 14;287(38):31983-93. doi: 10.1074/jbc.M112.374751. Epub 2012 Jul 26. J Biol Chem. 2012. PMID: 22843692 Free PMC article.
Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma.
Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, Malinowska A, Czerwoniec A, Barankiewicz J, Domagala A, Chlebowska J, Prochorec-Sobieszek M, Winiarska M, Ostaszewski R, Gwizdalska I, Golab J, Nowis D, Firczuk M. Trzeciecka A, et al. Among authors: muchowicz a. Oncotarget. 2016 Jan 12;7(2):1717-31. doi: 10.18632/oncotarget.6435. Oncotarget. 2016. PMID: 26636537 Free PMC article.
Inhibition of thioredoxin-dependent H2O2 removal sensitizes malignant B-cells to pharmacological ascorbate.
Graczyk-Jarzynka A, Goral A, Muchowicz A, Zagozdzon R, Winiarska M, Bajor M, Trzeciecka A, Fidyt K, Krupka JA, Cyran J, Szczygiel K, Efremov DG, Gobessi S, Jagielski A, Siudakowska K, Bobrowicz M, Klopotowska M, Barankiewicz J, Malenda A, Lech-Maranda E, Miazek-Zapala N, Skarzynski PH, Domagala A, Golab J, Firczuk M. Graczyk-Jarzynka A, et al. Among authors: muchowicz a. Redox Biol. 2019 Feb;21:101062. doi: 10.1016/j.redox.2018.11.020. Epub 2018 Nov 29. Redox Biol. 2019. PMID: 30576925 Free PMC article.
A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia.
Goral A, Firczuk M, Fidyt K, Sledz M, Simoncello F, Siudakowska K, Pagano G, Moussay E, Paggetti J, Nowakowska P, Gobessi S, Barankiewicz J, Salomon-Perzynski A, Benvenuti F, Efremov DG, Juszczynski P, Lech-Maranda E, Muchowicz A. Goral A, et al. Among authors: muchowicz a. Front Immunol. 2022 Feb 28;13:781364. doi: 10.3389/fimmu.2022.781364. eCollection 2022. Front Immunol. 2022. PMID: 35296093 Free PMC article.
Inhibition of protein disulfide isomerase induces differentiation of acute myeloid leukemia cells.
Chlebowska-Tuz J, Sokolowska O, Gaj P, Lazniewski M, Firczuk M, Borowiec K, Sas-Nowosielska H, Bajor M, Malinowska A, Muchowicz A, Ramji K, Stawinski P, Sobczak M, Pilch Z, Rodziewicz-Lurzynska A, Zajac M, Giannopoulos K, Juszczynski P, Basak GW, Plewczynski D, Ploski R, Golab J, Nowis D. Chlebowska-Tuz J, et al. Among authors: muchowicz a. Haematologica. 2018 Nov;103(11):1843-1852. doi: 10.3324/haematol.2018.190231. Epub 2018 Jul 12. Haematologica. 2018. PMID: 30002127 Free PMC article.
38 results