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Page 1
Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
Pancera M, Lai YT, Bylund T, Druz A, Narpala S, O'Dell S, Schön A, Bailer RT, Chuang GY, Geng H, Louder MK, Rawi R, Soumana DI, Finzi A, Herschhorn A, Madani N, Sodroski J, Freire E, Langley DR, Mascola JR, McDermott AB, Kwong PD. Pancera M, et al. Among authors: madani n. Nat Chem Biol. 2017 Oct;13(10):1115-1122. doi: 10.1038/nchembio.2460. Epub 2017 Aug 21. Nat Chem Biol. 2017. PMID: 28825711 Free PMC article.
Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions.
Biorn AC, Cocklin S, Madani N, Si Z, Ivanovic T, Samanen J, Van Ryk DI, Pantophlet R, Burton DR, Freire E, Sodroski J, Chaiken IM. Biorn AC, et al. Among authors: madani n. Biochemistry. 2004 Feb 24;43(7):1928-38. doi: 10.1021/bi035088i. Biochemistry. 2004. PMID: 14967033
Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins.
Si Z, Madani N, Cox JM, Chruma JJ, Klein JC, Schön A, Phan N, Wang L, Biorn AC, Cocklin S, Chaiken I, Freire E, Smith AB 3rd, Sodroski JG. Si Z, et al. Among authors: madani n. Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):5036-41. doi: 10.1073/pnas.0307953101. Epub 2004 Mar 29. Proc Natl Acad Sci U S A. 2004. PMID: 15051887 Free PMC article.
Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1.
Gopi H, Umashankara M, Pirrone V, LaLonde J, Madani N, Tuzer F, Baxter S, Zentner I, Cocklin S, Jawanda N, Miller SR, Schön A, Klein JC, Freire E, Krebs FC, Smith AB, Sodroski J, Chaiken I. Gopi H, et al. Among authors: madani n. J Med Chem. 2008 May 8;51(9):2638-47. doi: 10.1021/jm070814r. Epub 2008 Apr 11. J Med Chem. 2008. PMID: 18402432 Free PMC article.
Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.
Madani N, Schön A, Princiotto AM, Lalonde JM, Courter JR, Soeta T, Ng D, Wang L, Brower ET, Xiang SH, Kwon YD, Huang CC, Wyatt R, Kwong PD, Freire E, Smith AB 3rd, Sodroski J. Madani N, et al. Structure. 2008 Nov 12;16(11):1689-701. doi: 10.1016/j.str.2008.09.005. Structure. 2008. PMID: 19000821 Free PMC article.
206 results