Shea MA - Search Results

1

Backbone resonance assignments of complexes of human voltage-dependent sodium channel Na_V1.2 IQ motif peptide bound to apo calmodulin and to the C-domain fragment of apo calmodulin.

Mahling R, Kilpatrick AM, Shea MA. Mahling R, et al. Among authors: shea ma. Biomol NMR Assign. 2017 Oct;11(2):297-303. doi: 10.1007/s12104-017-9767-2. Epub 2017 Aug 19. Biomol NMR Assign. 2017. PMID: 28823028 Free PMC article.

2

Calcium-dependent energetics of calmodulin domain interactions with regulatory regions of the Ryanodine Receptor Type 1 (RyR1).

Newman RA, Sorensen BR, Kilpatrick AM, Shea MA. Newman RA, et al. Among authors: shea ma. Biophys Chem. 2014 Sep-Oct;193-194:35-49. doi: 10.1016/j.bpc.2014.07.004. Epub 2014 Jul 30. Biophys Chem. 2014. PMID: 25145833 Free PMC article.

3

Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel Na_V1.2.

Hovey L, Fowler CA, Mahling R, Lin Z, Miller MS, Marx DC, Yoder JB, Kim EH, Tefft KM, Waite BC, Feldkamp MD, Yu L, Shea MA. Hovey L, et al. Among authors: shea ma. Biophys Chem. 2017 May;224:1-19. doi: 10.1016/j.bpc.2017.02.006. Epub 2017 Mar 9. Biophys Chem. 2017. PMID: 28343066 Free PMC article.

4

Backbone resonance assignments of complexes of apo human calmodulin bound to IQ motif peptides of voltage-dependent sodium channels Na_V1.1, Na_V1.4 and Na_V1.7.

Isbell HM, Kilpatrick AM, Lin Z, Mahling R, Shea MA. Isbell HM, et al. Among authors: shea ma. Biomol NMR Assign. 2018 Oct;12(2):283-289. doi: 10.1007/s12104-018-9824-5. Epub 2018 May 4. Biomol NMR Assign. 2018. PMID: 29728980 Free PMC article.

5

Ca²⁺-saturated calmodulin binds tightly to the N-terminal domain of A-type fibroblast growth factor homologous factors.

Mahling R, Rahlf CR, Hansen SC, Hayden MR, Shea MA. Mahling R, et al. Among authors: shea ma. J Biol Chem. 2021 Jan-Jun;296:100458. doi: 10.1016/j.jbc.2021.100458. Epub 2021 Feb 24. J Biol Chem. 2021. PMID: 33639159 Free PMC article.

6

Na_V1.2 EFL domain allosterically enhances Ca²⁺ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.

Mahling R, Hovey L, Isbell HM, Marx DC, Miller MS, Kilpatrick AM, Weaver LD, Yoder JB, Kim EH, Andresen CNJ, Li S, Shea MA. Mahling R, et al. Among authors: shea ma. Structure. 2021 Dec 2;29(12):1339-1356.e7. doi: 10.1016/j.str.2021.03.002. Epub 2021 Mar 25. Structure. 2021. PMID: 33770503 Free PMC article.

7

Backbone and side-chain resonance assignments of (Ca²⁺)₄-calmodulin bound to beta calcineurin A CaMBD peptide.

Fowler CA, Núñez Hernandez MF, O'Donnell SE, Yu L, Shea MA. Fowler CA, et al. Among authors: shea ma. Biomol NMR Assign. 2017 Oct;11(2):275-280. doi: 10.1007/s12104-017-9762-7. Epub 2017 Aug 16. Biomol NMR Assign. 2017. PMID: 28815458 Free PMC article.

8

Structural and energetic determinants of apo calmodulin binding to the IQ motif of the Na(V)1.2 voltage-dependent sodium channel.

Feldkamp MD, Yu L, Shea MA. Feldkamp MD, et al. Among authors: shea ma. Structure. 2011 May 11;19(5):733-47. doi: 10.1016/j.str.2011.02.009. Structure. 2011. PMID: 21439835 Free PMC article.

9

The neuronal voltage-dependent sodium channel type II IQ motif lowers the calcium affinity of the C-domain of calmodulin.

Theoharis NT, Sorensen BR, Theisen-Toupal J, Shea MA. Theoharis NT, et al. Among authors: shea ma. Biochemistry. 2008 Jan 8;47(1):112-23. doi: 10.1021/bi7013129. Epub 2007 Dec 8. Biochemistry. 2008. PMID: 18067319

10

Recognition of β-calcineurin by the domains of calmodulin: thermodynamic and structural evidence for distinct roles.

O'Donnell SE, Yu L, Fowler CA, Shea MA. O'Donnell SE, et al. Among authors: shea ma. Proteins. 2011 Mar;79(3):765-86. doi: 10.1002/prot.22917. Epub 2010 Dec 6. Proteins. 2011. PMID: 21287611 Free PMC article.

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