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Page 1
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors.
Nawaz A, Aminuddin A, Kado T, Takikawa A, Yamamoto S, Tsuneyama K, Igarashi Y, Ikutani M, Nishida Y, Nagai Y, Takatsu K, Imura J, Sasahara M, Okazaki Y, Ueki K, Okamura T, Tokuyama K, Ando A, Matsumoto M, Mori H, Nakagawa T, Kobayashi N, Saeki K, Usui I, Fujisaka S, Tobe K. Nawaz A, et al. Among authors: tokuyama k. Nat Commun. 2017 Aug 18;8(1):286. doi: 10.1038/s41467-017-00231-1. Nat Commun. 2017. PMID: 28819169 Free PMC article.
Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.
Sasako T, Ohsugi M, Kubota N, Itoh S, Okazaki Y, Terai A, Kubota T, Yamashita S, Nakatsukasa K, Kamura T, Iwayama K, Tokuyama K, Kiyonari H, Furuta Y, Shibahara J, Fukayama M, Enooku K, Okushin K, Tsutsumi T, Tateishi R, Tobe K, Asahara H, Koike K, Kadowaki T, Ueki K. Sasako T, et al. Among authors: tokuyama k. Nat Commun. 2019 Feb 27;10(1):947. doi: 10.1038/s41467-019-08591-6. Nat Commun. 2019. PMID: 30814508 Free PMC article.
Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway.
Nishida Y, Nawaz A, Kado T, Takikawa A, Igarashi Y, Onogi Y, Wada T, Sasaoka T, Yamamoto S, Sasahara M, Imura J, Tokuyama K, Usui I, Nakagawa T, Fujisaka S, Kunimasa Y, Tobe K. Nishida Y, et al. Among authors: tokuyama k. J Cachexia Sarcopenia Muscle. 2020 Feb;11(1):241-258. doi: 10.1002/jcsm.12530. Epub 2020 Jan 31. J Cachexia Sarcopenia Muscle. 2020. PMID: 32003547 Free PMC article.
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions.
Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada-Iwabu M, Kawamoto S, Kubota N, Kubota T, Ito Y, Kamon J, Tsuchida A, Kumagai K, Kozono H, Hada Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Awazawa M, Takamoto I, Froguel P, Hara K, Tobe K, Nagai R, Ueki K, Kadowaki T. Yamauchi T, et al. Among authors: tokuyama k. Nat Med. 2007 Mar;13(3):332-9. doi: 10.1038/nm1557. Epub 2007 Feb 1. Nat Med. 2007. PMID: 17268472
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.
Okada-Iwabu M, Yamauchi T, Iwabu M, Honma T, Hamagami K, Matsuda K, Yamaguchi M, Tanabe H, Kimura-Someya T, Shirouzu M, Ogata H, Tokuyama K, Ueki K, Nagano T, Tanaka A, Yokoyama S, Kadowaki T. Okada-Iwabu M, et al. Among authors: tokuyama k. Nature. 2013 Nov 28;503(7477):493-9. doi: 10.1038/nature12656. Epub 2013 Oct 30. Nature. 2013. PMID: 24172895
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.
Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T. Kamei N, et al. Among authors: tokuyama k. J Biol Chem. 2006 Sep 8;281(36):26602-14. doi: 10.1074/jbc.M601284200. Epub 2006 Jun 29. J Biol Chem. 2006. PMID: 16809344 Free article.
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways.
Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T. Kubota N, et al. Among authors: tokuyama k. J Biol Chem. 2006 Mar 31;281(13):8748-55. doi: 10.1074/jbc.M505649200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431926 Free article.
Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.
Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T. Kubota N, et al. Among authors: tokuyama k. Cell Metab. 2008 Jul;8(1):49-64. doi: 10.1016/j.cmet.2008.05.007. Cell Metab. 2008. PMID: 18590692 Free article.
374 results