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MTG16 is a tumor suppressor in colitis-associated carcinoma.
McDonough EM, Barrett CW, Parang B, Mittal MK, Smith JJ, Bradley AM, Choksi YA, Coburn LA, Short SP, Thompson JJ, Zhang B, Poindexter SV, Fischer MA, Chen X, Li J, Revetta FL, Naik R, Washington MK, Rosen MJ, Hiebert SW, Wilson KT, Williams CS. McDonough EM, et al. Among authors: smith jj. JCI Insight. 2017 Aug 17;2(16):e78210. doi: 10.1172/jci.insight.78210. eCollection 2017 Aug 17. JCI Insight. 2017. PMID: 28814670 Free PMC article.
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer.
Smith JJ, Deane NG, Wu F, Merchant NB, Zhang B, Jiang A, Lu P, Johnson JC, Schmidt C, Bailey CE, Eschrich S, Kis C, Levy S, Washington MK, Heslin MJ, Coffey RJ, Yeatman TJ, Shyr Y, Beauchamp RD. Smith JJ, et al. Gastroenterology. 2010 Mar;138(3):958-68. doi: 10.1053/j.gastro.2009.11.005. Epub 2009 Nov 13. Gastroenterology. 2010. PMID: 19914252 Free PMC article. Clinical Trial.
BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma.
Williams CS, Zhang B, Smith JJ, Jayagopal A, Barrett CW, Pino C, Russ P, Presley SH, Peng D, Rosenblatt DO, Haselton FR, Yang JL, Washington MK, Chen X, Eschrich S, Yeatman TJ, El-Rifai W, Beauchamp RD, Chang MS. Williams CS, et al. Among authors: smith jj. J Clin Invest. 2011 Oct;121(10):4056-69. doi: 10.1172/JCI44228. Epub 2011 Sep 12. J Clin Invest. 2011. PMID: 21911938 Free PMC article.
Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.
Barrett CW, Smith JJ, Lu LC, Markham N, Stengel KR, Short SP, Zhang B, Hunt AA, Fingleton BM, Carnahan RH, Engel ME, Chen X, Beauchamp RD, Wilson KT, Hiebert SW, Reynolds AB, Williams CS. Barrett CW, et al. Among authors: smith jj. PLoS One. 2012;7(12):e51205. doi: 10.1371/journal.pone.0051205. Epub 2012 Dec 12. PLoS One. 2012. PMID: 23251453 Free PMC article.
BVES regulates c-Myc stability via PP2A and suppresses colitis-induced tumourigenesis.
Parang B, Kaz AM, Barrett CW, Short SP, Ning W, Keating CE, Mittal MK, Naik RD, Washington MK, Revetta FL, Smith JJ, Chen X, Wilson KT, Brand T, Bader DM, Tansey WP, Chen R, Brentnall TA, Grady WM, Williams CS. Parang B, et al. Among authors: smith jj. Gut. 2017 May;66(5):852-862. doi: 10.1136/gutjnl-2015-310255. Epub 2016 Jan 14. Gut. 2017. PMID: 28389570 Free PMC article.
Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer.
Means AL, Freeman TJ, Zhu J, Woodbury LG, Marincola-Smith P, Wu C, Meyer AR, Weaver CJ, Padmanabhan C, An H, Zi J, Wessinger BC, Chaturvedi R, Brown TD, Deane NG, Coffey RJ, Wilson KT, Smith JJ, Sawyers CL, Goldenring JR, Novitskiy SV, Washington MK, Shi C, Beauchamp RD. Means AL, et al. Among authors: smith jj. Cell Mol Gastroenterol Hepatol. 2018 May 24;6(3):257-276. doi: 10.1016/j.jcmgh.2018.05.006. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30109253 Free PMC article.
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas.
Nam KT, Lee HJ, Smith JJ, Lapierre LA, Kamath VP, Chen X, Aronow BJ, Yeatman TJ, Bhartur SG, Calhoun BC, Condie B, Manley NR, Beauchamp RD, Coffey RJ, Goldenring JR. Nam KT, et al. Among authors: smith jj. J Clin Invest. 2010 Mar;120(3):840-9. doi: 10.1172/JCI40728. Epub 2010 Feb 8. J Clin Invest. 2010. PMID: 20197623 Free PMC article.
995 results