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Escape of Tick-Borne Flavivirus from 2'-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness.
Eyer L, Kondo H, Zouharova D, Hirano M, Valdés JJ, Muto M, Kastl T, Kobayashi S, Haviernik J, Igarashi M, Kariwa H, Vaculovicova M, Cerny J, Kizek R, Kröger A, Lienenklaus S, Dejmek M, Nencka R, Palus M, Salat J, De Clercq E, Yoshii K, Ruzek D. Eyer L, et al. Among authors: de clercq e. J Virol. 2017 Oct 13;91(21):e01028-17. doi: 10.1128/JVI.01028-17. Print 2017 Nov 1. J Virol. 2017. PMID: 28814513 Free PMC article.
Complete genome sequence, taxonomic assignment, and comparative analysis of the untranslated regions of the Modoc virus, a flavivirus with no known vector.
Leyssen P, Charlier N, Lemey P, Billoir F, Vandamme AM, De Clercq E, de Lamballerie X, Neyts J. Leyssen P, et al. Among authors: de clercq e, de lamballerie x. Virology. 2002 Feb 1;293(1):125-40. doi: 10.1006/viro.2001.1241. Virology. 2002. PMID: 11853406 Free article.
Leyssen, A. Van Lommel, C. Drosten, H. Schmitz, E. De Clercq, and J. Neyts, 2001, Virology 279, 27-37). We now present the coding and noncoding sequence of MODV. ...The deduced gene order of the single open reading frame is C-prM-E-NS1-NS2A-NS2B-NS3-NS …
Leyssen, A. Van Lommel, C. Drosten, H. Schmitz, E. De Clercq, and J. Neyts, 2001, Virology 279, 27-37). We now present …
Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations.
Fikkert V, Van Maele B, Vercammen J, Hantson A, Van Remoortel B, Michiels M, Gurnari C, Pannecouque C, De Maeyer M, Engelborghs Y, De Clercq E, Debyser Z, Witvrouw M. Fikkert V, et al. Among authors: de clercq e, de maeyer m. J Virol. 2003 Nov;77(21):11459-70. doi: 10.1128/jvi.77.21.11459-11470.2003. J Virol. 2003. PMID: 14557631 Free PMC article.
Pluymers, B. Van Maele, V. Tetz, P. Cherepanov, E. De Clercq, M. Witvrouw, and Z. Debyser, Curr. Biol. 12:1169-1177, 2002). Antiviral resistance was also studied at the level of recombinant integrase. ...
Pluymers, B. Van Maele, V. Tetz, P. Cherepanov, E. De Clercq, M. Witvrouw, and Z. Debyser, Curr. Biol. 12:1169-1177, 20 …
The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.
Auwerx J, Stevens M, Van Rompay AR, Bird LE, Ren J, De Clercq E, Oberg B, Stammers DK, Karlsson A, Balzarini J. Auwerx J, et al. Among authors: de clercq e. J Virol. 2004 Jul;78(14):7427-37. doi: 10.1128/JVI.78.14.7427-7437.2004. J Virol. 2004. PMID: 15220416 Free PMC article.
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Paeshuyse J, Leyssen P, Mabery E, Boddeker N, Vrancken R, Froeyen M, Ansari IH, Dutartre H, Rozenski J, Gil LH, Letellier C, Lanford R, Canard B, Koenen F, Kerkhofs P, Donis RO, Herdewijn P, Watson J, De Clercq E, Puerstinger G, Neyts J. Paeshuyse J, et al. Among authors: de clercq e. J Virol. 2006 Jan;80(1):149-60. doi: 10.1128/JVI.80.1.149-160.2006. J Virol. 2006. PMID: 16352539 Free PMC article.
2,294 results