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Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit.
Arima Y, Ohki T, Nishikawa N, Higuchi K, Ota M, Tanaka Y, Nio-Kobayashi J, Elfeky M, Sakai R, Mori Y, Kawamoto T, Stofkova A, Sakashita Y, Morimoto Y, Kuwatani M, Iwanaga T, Yoshioka Y, Sakamoto N, Yoshimura A, Takiguchi M, Sakoda S, Prinz M, Kamimura D, Murakami M. Arima Y, et al. Among authors: yoshimura a. Elife. 2017 Aug 15;6:e25517. doi: 10.7554/eLife.25517. Elife. 2017. PMID: 28809157 Free PMC article.
A novel JAK-STAT inhibitor, 2-[(3-Carbamoyl-2-thienyl)amino]-2-oxoethyl(2,6-dichlorophenyl)acetate, suppresses helper T cell differentiation in vitro and collagen-induced arthritis in vivo.
Asakawa M, Yoshida H, Sakai R, Saeki K, Okada M, Kanamori M, Kotani H, Wei X, Yoshimura A. Asakawa M, et al. Among authors: yoshimura a. Biochem Biophys Res Commun. 2015 Dec 25;468(4):766-73. doi: 10.1016/j.bbrc.2015.11.030. Epub 2015 Nov 10. Biochem Biophys Res Commun. 2015. PMID: 26562526
Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery.
Ito M, Komai K, Mise-Omata S, Iizuka-Koga M, Noguchi Y, Kondo T, Sakai R, Matsuo K, Nakayama T, Yoshie O, Nakatsukasa H, Chikuma S, Shichita T, Yoshimura A. Ito M, et al. Among authors: yoshimura a. Nature. 2019 Jan;565(7738):246-250. doi: 10.1038/s41586-018-0824-5. Epub 2019 Jan 2. Nature. 2019. PMID: 30602786
Tissue regulatory T cells and neural repair.
Ito M, Komai K, Nakamura T, Srirat T, Yoshimura A. Ito M, et al. Among authors: yoshimura a. Int Immunol. 2019 May 21;31(6):361-369. doi: 10.1093/intimm/dxz031. Int Immunol. 2019. PMID: 30893423 Review.
[Role of T lymphocytes in ischemic brain injury].
Shichita T, Konoeda F, Yoshimura A. Shichita T, et al. Among authors: yoshimura a. Rinsho Shinkeigaku. 2010 Nov;50(11):878-80. doi: 10.5692/clinicalneurol.50.878. Rinsho Shinkeigaku. 2010. PMID: 21921486 Review. Japanese.
1,535 results