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Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation.
Brocke-Heidrich K, Kretzschmar AK, Pfeifer G, Henze C, Löffler D, Koczan D, Thiesen HJ, Burger R, Gramatzki M, Horn F. Brocke-Heidrich K, et al. Among authors: gramatzki m. Blood. 2004 Jan 1;103(1):242-51. doi: 10.1182/blood-2003-04-1048. Epub 2003 Sep 11. Blood. 2004. PMID: 12969979 Free article.
Functional significance of novel neurotrophin-1/B cell-stimulating factor-3 (cardiotrophin-like cytokine) for human myeloma cell growth and survival.
Burger R, Bakker F, Guenther A, Baum W, Schmidt-Arras D, Hideshima T, Tai YT, Shringarpure R, Catley L, Senaldi G, Gramatzki M, Anderson KC. Burger R, et al. Among authors: gramatzki m. Br J Haematol. 2003 Dec;123(5):869-78. doi: 10.1046/j.1365-2141.2003.04686.x. Br J Haematol. 2003. PMID: 14632778 Free article.
Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer.
Löffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermüller J, Kretzschmar AK, Burger R, Gramatzki M, Blumert C, Bauer K, Cvijic H, Ullmann AK, Stadler PF, Horn F. Löffler D, et al. Among authors: gramatzki m. Blood. 2007 Aug 15;110(4):1330-3. doi: 10.1182/blood-2007-03-081133. Epub 2007 May 11. Blood. 2007. PMID: 17496199 Free article.
CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains.
Meyer D, Seth S, Albrecht J, Maier MK, du Pasquier L, Ravens I, Dreyer L, Burger R, Gramatzki M, Schwinzer R, Kremmer E, Foerster R, Bernhardt G. Meyer D, et al. Among authors: gramatzki m. J Biol Chem. 2009 Jan 23;284(4):2235-44. doi: 10.1074/jbc.M807698200. Epub 2008 Dec 4. J Biol Chem. 2009. PMID: 19056733 Free article.
Janus kinase inhibitor INCB20 has antiproliferative and apoptotic effects on human myeloma cells in vitro and in vivo.
Burger R, Le Gouill S, Tai YT, Shringarpure R, Tassone P, Neri P, Podar K, Catley L, Hideshima T, Chauhan D, Caulder E, Neilan CL, Vaddi K, Li J, Gramatzki M, Fridman JS, Anderson KC. Burger R, et al. Among authors: gramatzki m. Mol Cancer Ther. 2009 Jan;8(1):26-35. doi: 10.1158/1535-7163.MCT-08-0149. Mol Cancer Ther. 2009. PMID: 19139110 Free PMC article.
196 results