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Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.
Brunello L, Slabaugh JL, Radwanski PB, Ho HT, Belevych AE, Lou Q, Chen H, Napolitano C, Lodola F, Priori SG, Fedorov VV, Volpe P, Fill M, Janssen PM, Györke S. Brunello L, et al. Among authors: radwanski pb. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10312-7. doi: 10.1073/pnas.1300052110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733959 Free PMC article.
Neuronal Na+ channel blockade suppresses arrhythmogenic diastolic Ca2+ release.
Radwański PB, Brunello L, Veeraraghavan R, Ho HT, Lou Q, Makara MA, Belevych AE, Anghelescu M, Priori SG, Volpe P, Hund TJ, Janssen PM, Mohler PJ, Bridge JH, Poelzing S, Györke S. Radwański PB, et al. Cardiovasc Res. 2015 Apr 1;106(1):143-52. doi: 10.1093/cvr/cvu262. Epub 2014 Dec 23. Cardiovasc Res. 2015. PMID: 25538156 Free PMC article.
Muscarinic Stimulation Facilitates Sarcoplasmic Reticulum Ca Release by Modulating Ryanodine Receptor 2 Phosphorylation Through Protein Kinase G and Ca/Calmodulin-Dependent Protein Kinase II.
Ho HT, Belevych AE, Liu B, Bonilla IM, Radwański PB, Kubasov IV, Valdivia HH, Schober K, Carnes CA, Györke S. Ho HT, et al. Among authors: radwanski pb. Hypertension. 2016 Nov;68(5):1171-1178. doi: 10.1161/HYPERTENSIONAHA.116.07666. Epub 2016 Sep 19. Hypertension. 2016. PMID: 27647848 Free PMC article. Review.
Neuronal Na+ Channels Are Integral Components of Pro-arrhythmic Na+/Ca2+ Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-adrenergic Stimulation.
Radwański PB, Ho HT, Veeraraghavan R, Brunello L, Liu B, Belevych AE, Unudurthi SD, Makara MA, Priori SG, Volpe P, Armoundas AA, Dillmann WH, Knollmann BC, Mohler PJ, Hund TJ, Györke S. Radwański PB, et al. JACC Basic Transl Sci. 2016 Jun;1(4):251-266. doi: 10.1016/j.jacbts.2016.04.004. JACC Basic Transl Sci. 2016. PMID: 27747307 Free PMC article.
40 results