Lei X - Search Results

1

Synthesis and biological evaluation of Aspergillomarasmine A derivatives as novel NDM-1 inhibitor to overcome antibiotics resistance.

Zhang J, Wang S, Wei Q, Guo Q, Bai Y, Yang S, Song F, Zhang L, Lei X. Zhang J, et al. Among authors: lei x. Bioorg Med Chem. 2017 Oct 1;25(19):5133-5141. doi: 10.1016/j.bmc.2017.07.025. Epub 2017 Jul 14. Bioorg Med Chem. 2017. PMID: 28784300

2

Total Synthesis and Structural Reassignment of Aspergillomarasmine A.

Liao D, Yang S, Wang J, Zhang J, Hong B, Wu F, Lei X. Liao D, et al. Among authors: lei x. Angew Chem Int Ed Engl. 2016 Mar 18;55(13):4291-5. doi: 10.1002/anie.201509960. Epub 2015 Nov 23. Angew Chem Int Ed Engl. 2016. PMID: 26592805

3

Access to the 2H-Tetrahydro-4,6-dioxo-1,2-oxazine Ring System from Nitrone via a Tandem Nucleophilic Addition and Transesterification Reaction.

Yang S, Liao D, Tian X, Lei X. Yang S, et al. Among authors: lei x. Org Lett. 2016 Feb 5;18(3):376-9. doi: 10.1021/acs.orglett.5b03374. Epub 2016 Jan 12. Org Lett. 2016. PMID: 26849452

4

Identification of spirobisnaphthalene derivatives with anti-tumor activities from the endophytic fungus Rhytidhysteron rufulum AS21B.

Siridechakorn I, Yue Z, Mittraphab Y, Lei X, Pudhom K. Siridechakorn I, et al. Among authors: lei x. Bioorg Med Chem. 2017 Jun 1;25(11):2878-2882. doi: 10.1016/j.bmc.2017.02.054. Epub 2017 Feb 27. Bioorg Med Chem. 2017. PMID: 28274675

5

Small molecule enabled chemical biology and drug discovery.

Lei X. Lei X. Bioorg Med Chem. 2017 Jun 1;25(11):2815-2816. doi: 10.1016/j.bmc.2017.05.025. Bioorg Med Chem. 2017. PMID: 28532738 No abstract available.

6

Total Syntheses of Natural Metallophores Staphylopine and Aspergillomarasmine A.

Zhang J, Wang S, Bai Y, Guo Q, Zhou J, Lei X. Zhang J, et al. Among authors: lei x. J Org Chem. 2017 Dec 15;82(24):13643-13648. doi: 10.1021/acs.joc.7b02342. Epub 2017 Nov 30. J Org Chem. 2017. PMID: 29115130

7

Development of an effective fluorescence probe for discovery of aminopeptidase inhibitors to suppress biofilm formation.

Zhao T, Zhang J, Tang M, Ma LZ, Lei X. Zhao T, et al. Among authors: lei x. J Antibiot (Tokyo). 2019 Jun;72(6):461-468. doi: 10.1038/s41429-019-0166-z. Epub 2019 Mar 20. J Antibiot (Tokyo). 2019. PMID: 30894675

8

De novo synthesis, structural assignment and biological evaluation of pseudopaline, a metallophore produced by Pseudomonas aeruginosa.

Zhang J, Zhao T, Yang R, Siridechakorn I, Wang S, Guo Q, Bai Y, Shen HC, Lei X. Zhang J, et al. Among authors: lei x. Chem Sci. 2019 May 30;10(27):6635-6641. doi: 10.1039/c9sc01405e. eCollection 2019 Jul 21. Chem Sci. 2019. PMID: 31367316 Free PMC article.

9

Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores.

McFarlane JS, Zhang J, Wang S, Lei X, Moran GR, Lamb AL. McFarlane JS, et al. Among authors: lei x. J Biol Chem. 2019 Nov 22;294(47):17988-18001. doi: 10.1074/jbc.RA119.011059. Epub 2019 Oct 15. J Biol Chem. 2019. PMID: 31615895 Free PMC article.

10

An Arabidopsis Secondary Metabolite Directly Targets Expression of the Bacterial Type III Secretion System to Inhibit Bacterial Virulence.

Wang W, Yang J, Zhang J, Liu YX, Tian C, Qu B, Gao C, Xin P, Cheng S, Zhang W, Miao P, Li L, Zhang X, Chu J, Zuo J, Li J, Bai Y, Lei X, Zhou JM. Wang W, et al. Among authors: lei x. Cell Host Microbe. 2020 Apr 8;27(4):601-613.e7. doi: 10.1016/j.chom.2020.03.004. Cell Host Microbe. 2020. PMID: 32272078 Free article.

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