The Streptococcus agalactiae complement interfering protein combines multiple complement-inhibitory mechanisms by interacting with both C4 and C3 ligands.
Giussani S, Pietrocola G, Donnarumma D, Norais N, Speziale P, Fabbrini M, Margarit I.
Giussani S, et al. Among authors: donnarumma d.
FASEB J. 2019 Mar;33(3):4448-4457. doi: 10.1096/fj.201801991R. Epub 2018 Dec 19.
FASEB J. 2019.
PMID: 30566365
Free PMC article.
The data obtained reveal a new role for this GBS polypeptide at the interface between the innate and adaptive immune responses, adding a new member to the growing list of virulence factors secreted by gram-positive pathogens that incorporate multiple immunomodulatory functions.-G …
The data obtained reveal a new role for this GBS polypeptide at the interface between the innate and adaptive immune responses, adding a new …