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Page 1
Epiregulin and EGFR interactions are involved in pain processing.
Martin LJ, Smith SB, Khoutorsky A, Magnussen CA, Samoshkin A, Sorge RE, Cho C, Yosefpour N, Sivaselvachandran S, Tohyama S, Cole T, Khuong TM, Mir E, Gibson DG, Wieskopf JS, Sotocinal SG, Austin JS, Meloto CB, Gitt JH, Gkogkas C, Sonenberg N, Greenspan JD, Fillingim RB, Ohrbach R, Slade GD, Knott C, Dubner R, Nackley AG, Ribeiro-da-Silva A, Neely GG, Maixner W, Zaykin DV, Mogil JS, Diatchenko L. Martin LJ, et al. Among authors: sorge re. J Clin Invest. 2017 Sep 1;127(9):3353-3366. doi: 10.1172/JCI87406. Epub 2017 Aug 7. J Clin Invest. 2017. PMID: 28783046 Free PMC article.
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
Sorge RE, Trang T, Dorfman R, Smith SB, Beggs S, Ritchie J, Austin JS, Zaykin DV, Vander Meulen H, Costigan M, Herbert TA, Yarkoni-Abitbul M, Tichauer D, Livneh J, Gershon E, Zheng M, Tan K, John SL, Slade GD, Jordan J, Woolf CJ, Peltz G, Maixner W, Diatchenko L, Seltzer Z, Salter MW, Mogil JS. Sorge RE, et al. Nat Med. 2012 Mar 25;18(4):595-9. doi: 10.1038/nm.2710. Nat Med. 2012. PMID: 22447075 Free PMC article.
eIF2α phosphorylation controls thermal nociception.
Khoutorsky A, Sorge RE, Prager-Khoutorsky M, Pawlowski SA, Longo G, Jafarnejad SM, Tahmasebi S, Martin LJ, Pitcher MH, Gkogkas CG, Sharif-Naeini R, Ribeiro-da-Silva A, Bourque CW, Cervero F, Mogil JS, Sonenberg N. Khoutorsky A, et al. Among authors: sorge re. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11949-11954. doi: 10.1073/pnas.1614047113. Epub 2016 Oct 3. Proc Natl Acad Sci U S A. 2016. PMID: 27698114 Free PMC article.
Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction.
Mogil JS, Sorge RE, LaCroix-Fralish ML, Smith SB, Fortin A, Sotocinal SG, Ritchie J, Austin JS, Schorscher-Petcu A, Melmed K, Czerminski J, Bittong RA, Mokris JB, Neubert JK, Campbell CM, Edwards RR, Campbell JN, Crawley JN, Lariviere WR, Wallace MR, Sternberg WF, Balaban CD, Belfer I, Fillingim RB. Mogil JS, et al. Among authors: sorge re. Nat Neurosci. 2011 Oct 23;14(12):1569-73. doi: 10.1038/nn.2941. Nat Neurosci. 2011. PMID: 22019732 Free PMC article.
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.
Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, Slepian PM, Clarke S, Drenan RM, Janes J, Al Sharari S, Segall SK, Aasvang EK, Lai W, Bittner R, Richards CI, Slade GD, Kehlet H, Walker J, Maskos U, Changeux JP, Devor M, Maixner W, Diatchenko L, Belfer I, Dougherty DA, Su AI, Lummis SC, Imad Damaj M, Lester HA, Patapoutian A, Mogil JS. Wieskopf JS, et al. Among authors: sorge re. Sci Transl Med. 2015 May 13;7(287):287ra72. doi: 10.1126/scitranslmed.3009986. Sci Transl Med. 2015. PMID: 25972004 Free PMC article.
Different immune cells mediate mechanical pain hypersensitivity in male and female mice.
Sorge RE, Mapplebeck JC, Rosen S, Beggs S, Taves S, Alexander JK, Martin LJ, Austin JS, Sotocinal SG, Chen D, Yang M, Shi XQ, Huang H, Pillon NJ, Bilan PJ, Tu Y, Klip A, Ji RR, Zhang J, Salter MW, Mogil JS. Sorge RE, et al. Nat Neurosci. 2015 Aug;18(8):1081-3. doi: 10.1038/nn.4053. Epub 2015 Jun 29. Nat Neurosci. 2015. PMID: 26120961 Free PMC article.
Translational control of nociception via 4E-binding protein 1.
Khoutorsky A, Bonin RP, Sorge RE, Gkogkas CG, Pawlowski SA, Jafarnejad SM, Pitcher MH, Alain T, Perez-Sanchez J, Salter EW, Martin L, Ribeiro-da-Silva A, De Koninck Y, Cervero F, Mogil JS, Sonenberg N. Khoutorsky A, et al. Among authors: sorge re. Elife. 2015 Dec 18;4:e12002. doi: 10.7554/eLife.12002. Elife. 2015. PMID: 26678009 Free PMC article.
74 results