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Page 1
Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor.
Roymans D, Alnajjar SS, Battles MB, Sitthicharoenchai P, Furmanova-Hollenstein P, Rigaux P, Berg JVD, Kwanten L, Ginderen MV, Verheyen N, Vranckx L, Jaensch S, Arnoult E, Voorzaat R, Gallup JM, Larios-Mora A, Crabbe M, Huntjens D, Raboisson P, Langedijk JP, Ackermann MR, McLellan JS, Vendeville S, Koul A. Roymans D, et al. Among authors: voorzaat r. Nat Commun. 2017 Aug 1;8(1):167. doi: 10.1038/s41467-017-00170-x. Nat Commun. 2017. PMID: 28761099 Free PMC article.
Stabilizing the closed SARS-CoV-2 spike trimer.
Juraszek J, Rutten L, Blokland S, Bouchier P, Voorzaat R, Ritschel T, Bakkers MJG, Renault LLR, Langedijk JPM. Juraszek J, et al. Among authors: voorzaat r. Nat Commun. 2021 Jan 11;12(1):244. doi: 10.1038/s41467-020-20321-x. Nat Commun. 2021. PMID: 33431842 Free PMC article.
A foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responses.
Bakkers MJG, Cox F, Koornneef A, Yu X, van Overveld D, Le L, van den Hoogen W, Vaneman J, Thoma A, Voorzaat R, Tettero L, Juraszek J, van der Fits L, Zahn R, Langedijk JPM. Bakkers MJG, et al. Among authors: voorzaat r. Nat Microbiol. 2024 Dec;9(12):3254-3267. doi: 10.1038/s41564-024-01860-1. Epub 2024 Nov 20. Nat Microbiol. 2024. PMID: 39567664 Free PMC article.
Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer.
Bakkers MJG, Ritschel T, Tiemessen M, Dijkman J, Zuffianò AA, Yu X, van Overveld D, Le L, Voorzaat R, van Haaren MM, de Man M, Tamara S, van der Fits L, Zahn R, Juraszek J, Langedijk JPM. Bakkers MJG, et al. Among authors: voorzaat r. Nat Commun. 2024 Jul 25;15(1):6270. doi: 10.1038/s41467-024-50659-5. Nat Commun. 2024. PMID: 39054318 Free PMC article.