van der Sluis R - Search Results

1

New insights into the catalytic mechanism of human glycine N-acyltransferase.

van der Sluis R, Ungerer V, Nortje C, A van Dijk A, Erasmus E. van der Sluis R, et al. J Biochem Mol Toxicol. 2017 Nov;31(11). doi: 10.1002/jbt.21963. Epub 2017 Jul 31. J Biochem Mol Toxicol. 2017. PMID: 28759163

2

Characterisation of the influence of genetic variations on the enzyme activity of a recombinant human glycine N-acyltransferase.

van der Sluis R, Badenhorst CP, van der Westhuizen FH, van Dijk AA. van der Sluis R, et al. Among authors: van der westhuizen fh, van dijk aa. Gene. 2013 Feb 25;515(2):447-53. doi: 10.1016/j.gene.2012.12.003. Epub 2012 Dec 10. Gene. 2013. PMID: 23237781

3

Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.

Badenhorst CP, van der Sluis R, Erasmus E, van Dijk AA. Badenhorst CP, et al. Among authors: van dijk aa, van der sluis r. Expert Opin Drug Metab Toxicol. 2013 Sep;9(9):1139-53. doi: 10.1517/17425255.2013.796929. Epub 2013 May 8. Expert Opin Drug Metab Toxicol. 2013. PMID: 23650932 Review.

4

A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids.

Badenhorst CP, Erasmus E, van der Sluis R, Nortje C, van Dijk AA. Badenhorst CP, et al. Among authors: van dijk aa, van der sluis r. Drug Metab Rev. 2014 Aug;46(3):343-61. doi: 10.3109/03602532.2014.908903. Epub 2014 Apr 22. Drug Metab Rev. 2014. PMID: 24754494 Review.

5

Conservation of the coding regions of the glycine N-acyltransferase gene further suggests that glycine conjugation is an essential detoxification pathway.

van der Sluis R, Badenhorst CP, Erasmus E, van Dyk E, van der Westhuizen FH, van Dijk AA. van der Sluis R, et al. Among authors: van dyk e, van der westhuizen fh, van dijk aa. Gene. 2015 Oct 15;571(1):126-34. doi: 10.1016/j.gene.2015.06.081. Epub 2015 Jul 3. Gene. 2015. PMID: 26149650

6

The Use of p-Aminobenzoic Acid as a Probe Substance for the Targeted Profiling of Glycine Conjugation.

Nortje C, van der Sluis R, van Dijk AA, Erasmus E. Nortje C, et al. Among authors: van dijk aa, van der sluis r. J Biochem Mol Toxicol. 2016 Mar;30(3):136-47. doi: 10.1002/jbt.21772. Epub 2015 Oct 20. J Biochem Mol Toxicol. 2016. PMID: 26484797

7

Xenobiotic/medium chain fatty acid: CoA ligase - a critical review on its role in fatty acid metabolism and the detoxification of benzoic acid and aspirin.

van der Sluis R, Erasmus E. van der Sluis R, et al. Expert Opin Drug Metab Toxicol. 2016 Oct;12(10):1169-79. doi: 10.1080/17425255.2016.1206888. Epub 2016 Jul 15. Expert Opin Drug Metab Toxicol. 2016. PMID: 27351777 Review.

8

Functional Characterisation of Three Glycine N-Acyltransferase Variants and the Effect on Glycine Conjugation to Benzoyl-CoA.

Rohwer JM, Schutte C, van der Sluis R. Rohwer JM, et al. Among authors: van der sluis r. Int J Mol Sci. 2021 Mar 18;22(6):3129. doi: 10.3390/ijms22063129. Int J Mol Sci. 2021. PMID: 33803916 Free PMC article.

9

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

van der Sluis R. van der Sluis R. Mol Genet Genomics. 2018 Oct;293(5):1279-1292. doi: 10.1007/s00438-018-1460-3. Epub 2018 Jun 14. Mol Genet Genomics. 2018. PMID: 29948332

10

The glycine N-acyltransferases, GLYAT and GLYATL1, contribute to the detoxification of isovaleryl-CoA - an in-silico and in vitro validation.

Kühn S, Williams ME, Dercksen M, Sass JO, van der Sluis R. Kühn S, et al. Among authors: van der sluis r. Comput Struct Biotechnol J. 2023 Jan 31;21:1236-1248. doi: 10.1016/j.csbj.2023.01.041. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 36817957 Free PMC article.

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