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Page 1
Metabolic Profiling of CB1 Neutral Antagonists.
Seltzman HH, Maitra R, Bortoff K, Henson J, Reggio PH, Wesley D, Tam J. Seltzman HH, et al. Among authors: bortoff k. Methods Enzymol. 2017;593:199-215. doi: 10.1016/bs.mie.2017.06.025. Epub 2017 Jul 10. Methods Enzymol. 2017. PMID: 28750803 Free PMC article.
Discovery of a novel small molecule agonist scaffold for the APJ receptor.
Narayanan S, Maitra R, Deschamps JR, Bortoff K, Thomas JB, Zhang Y, Warner K, Vasukuttan V, Decker A, Runyon SP. Narayanan S, et al. Among authors: bortoff k. Bioorg Med Chem. 2016 Aug 15;24(16):3758-70. doi: 10.1016/j.bmc.2016.06.018. Epub 2016 Jun 11. Bioorg Med Chem. 2016. PMID: 27369451 Free PMC article.
Pyrazole antagonists of the CB1 receptor with reduced brain penetration.
Fulp A, Zhang Y, Bortoff K, Seltzman H, Snyder R, Wiethe R, Amato G, Maitra R. Fulp A, et al. Among authors: bortoff k. Bioorg Med Chem. 2016 Mar 1;24(5):1063-70. doi: 10.1016/j.bmc.2016.01.033. Epub 2016 Jan 18. Bioorg Med Chem. 2016. PMID: 26827137 Free PMC article.
Peripherally selective diphenyl purine antagonist of the CB1 receptor.
Fulp A, Bortoff K, Zhang Y, Snyder R, Fennell T, Marusich JA, Wiley JL, Seltzman H, Maitra R. Fulp A, et al. Among authors: bortoff k. J Med Chem. 2013 Oct 24;56(20):8066-72. doi: 10.1021/jm401129n. Epub 2013 Sep 27. J Med Chem. 2013. PMID: 24041123 Free PMC article.
Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma.
Lin N, Di C, Bortoff K, Fu J, Truszkowski P, Killela P, Duncan C, McLendon R, Bigner D, Gregory S, Adamson DC. Lin N, et al. Among authors: bortoff k. Mol Cancer Res. 2012 Feb;10(2):208-17. doi: 10.1158/1541-7786.MCR-10-0109. Epub 2012 Jan 12. Mol Cancer Res. 2012. PMID: 22241217 Free PMC article.
17 results