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Page 1
Isosorbide-based peptidomimetics as inhibitors of hepatitis C virus serine protease.
Portela AC, Barros TG, Lima CHDS, Dias LRS, Azevedo PHRA, Dantas ASCL, Mohana-Borges R, Ventura GT, Pinheiro S, Muri EMF. Portela AC, et al. Among authors: pinheiro s. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3661-3665. doi: 10.1016/j.bmcl.2017.07.027. Epub 2017 Jul 8. Bioorg Med Chem Lett. 2017. PMID: 28729054
Pseudo-peptides derived from isomannide: inhibitors of serine proteases.
Barros TG, Pinheiro S, Williamson JS, Tanuri A, Gomes M Jr, Pereira HS, Brindeiro RM, Neto JB, Antunes OA, Muri EM. Barros TG, et al. Among authors: pinheiro s. Amino Acids. 2010 Mar;38(3):701-9. doi: 10.1007/s00726-009-0273-4. Epub 2009 Mar 28. Amino Acids. 2010. PMID: 19330426
Isomannide derivatives as new class of inhibitors for human kallikrein 7.
Freitas RF, Teixeira TS, Barros TG, Santos JA, Kondo MY, Juliano MA, Juliano L, Blaber M, Antunes OA, Abrahão O Jr, Pinheiro S, Muri EM, Puzer L. Freitas RF, et al. Among authors: pinheiro s. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6072-5. doi: 10.1016/j.bmcl.2012.08.047. Epub 2012 Aug 21. Bioorg Med Chem Lett. 2012. PMID: 22959247
Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7.
Oliveira JP, Freitas RF, Melo LS, Barros TG, Santos JA, Juliano MA, Pinheiro S, Blaber M, Juliano L, Muri EM, Puzer L. Oliveira JP, et al. Among authors: pinheiro s. ACS Med Chem Lett. 2013 Dec 6;5(2):128-32. doi: 10.1021/ml4003698. eCollection 2014 Feb 13. ACS Med Chem Lett. 2013. PMID: 24900785 Free PMC article.
Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor.
Barros TG, Santos JAN, de Souza BEG, Sodero ACR, de Souza AMT, da Silva DP, Rodrigues CR, Pinheiro S, Dias LRS, Abrahim-Vieira B, Puzer L, Muri EMF. Barros TG, et al. Among authors: pinheiro s. Bioorg Med Chem Lett. 2017 Jan 15;27(2):314-318. doi: 10.1016/j.bmcl.2016.11.051. Epub 2016 Nov 18. Bioorg Med Chem Lett. 2017. PMID: 27914800
3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7.
de Souza AS, Pacheco BDC, Pinheiro S, Muri EMF, Dias LRS, Lima CHS, Garrett R, de Moraes MBM, de Souza BEG, Puzer L. de Souza AS, et al. Among authors: pinheiro s. Bioorg Med Chem Lett. 2019 May 1;29(9):1094-1098. doi: 10.1016/j.bmcl.2019.02.031. Epub 2019 Feb 27. Bioorg Med Chem Lett. 2019. PMID: 30833107
2H-1,2,3-Triazole-chalcones as novel cytotoxic agents against prostate cancer.
Pinheiro S, Pessôa JC, Pinheiro EMC, Muri EMF, Filho EV, Loureiro LB, Freitas MCR, Silva Junior CMD, Fiorot RG, Carneiro JWM, Rotamiro KM, Guimarães ARA, Rocha-Brito KJP, Greco SJ. Pinheiro S, et al. Among authors: pinheiro emc. Bioorg Med Chem Lett. 2020 Oct 1;30(19):127454. doi: 10.1016/j.bmcl.2020.127454. Epub 2020 Jul 28. Bioorg Med Chem Lett. 2020. PMID: 32736078
Molecular modeling of a phenyl-amidine class of NMDA receptor antagonists and the rational design of new triazolyl-amidine derivatives.
Abreu PA, Castro HC, Paes-de-Carvalho R, Rodrigues CR, Giongo V, Paixão IC, Santana MV, Ferreira JM, Caversan OM, Leão RA, Marins LM, Henriques AM, Farias FM, Albuquerque MG, Pinheiro S. Abreu PA, et al. Among authors: pinheiro s. Chem Biol Drug Des. 2013 Feb;81(2):185-97. doi: 10.1111/cbdd.12056. Epub 2012 Dec 17. Chem Biol Drug Des. 2013. PMID: 22985449
415 results