Kothare PA - Search Results

1

Leveraging a Clinical Phase Ib Proof-of-Concept Study for the GPR40 Agonist MK-8666 in Patients With Type 2 Diabetes for Model-Informed Phase II Dose Selection.

Krug AW, Vaddady P, Railkar RA, Musser BJ, Cote J, Ederveen A, Krefetz DG, DeNoia E, Free AL, Morrow L, Chakravarthy MV, Kauh E, Tatosian DA, Kothare PA. Krug AW, et al. Among authors: kothare pa. Clin Transl Sci. 2017 Sep;10(5):404-411. doi: 10.1111/cts.12479. Epub 2017 Jul 20. Clin Transl Sci. 2017. PMID: 28727908 Free PMC article. Clinical Trial.

2

Making Better Dose Decisions: Using Exposure-Response Modeling to Integrate Efficacy Outcome of Two Phase IIb Clinical Trials of Ubrogepant for Migraine Treatment.

Li CC, Voss T, Kowalski K, Yang B, Kleijn HJ, Jones CJ, Bosch R, Michelson D, DeAngelis M, Xu Y, Xie I, Kothare PA. Li CC, et al. Among authors: kothare pa. Clin Transl Sci. 2020 May;13(3):482-490. doi: 10.1111/cts.12730. Epub 2020 Jan 16. Clin Transl Sci. 2020. PMID: 31758661 Free PMC article. Clinical Trial.

3

Safety, tolerability, pharmacokinetics, and pharmacodynamics of exenatide once weekly in Japanese patients with type 2 diabetes.

Iwamoto K, Nasu R, Yamamura A, Kothare PA, Mace K, Wolka AM, Linnebjerg H. Iwamoto K, et al. Among authors: kothare pa. Endocr J. 2009;56(8):951-62. doi: 10.1507/endocrj.k09e-147. Epub 2009 Aug 25. Endocr J. 2009. PMID: 19706990 Free article. Clinical Trial.

4

Pharmacokinetics, pharmacodynamics, tolerability, and safety of exenatide in Japanese patients with type 2 diabetes mellitus.

Kothare PA, Linnebjerg H, Isaka Y, Uenaka K, Yamamura A, Yeo KP, de la Peña A, Teng CH, Mace K, Fineman M, Shigeta H, Sakata Y, Irie S. Kothare PA, et al. J Clin Pharmacol. 2008 Dec;48(12):1389-99. doi: 10.1177/0091270008323750. J Clin Pharmacol. 2008. PMID: 19047364 Clinical Trial.

5

Pharmacology and tolerability of a single dose of exenatide in adolescent patients with type 2 diabetes mellitus being treated with metformin: a randomized, placebo-controlled, single-blind, dose-escalation, crossover study.

Malloy J, Capparelli E, Gottschalk M, Guan X, Kothare P, Fineman M. Malloy J, et al. Clin Ther. 2009 Apr;31(4):806-15. doi: 10.1016/j.clinthera.2009.04.005. Clin Ther. 2009. PMID: 19446153 Clinical Trial.

6

Exenatide effects on statin pharmacokinetics and lipid response.

Kothare PA, Linnebjerg H, Skrivanek Z, Reddy S, Mace K, Pena A, Han J, Fineman M, Mitchell M. Kothare PA, et al. Int J Clin Pharmacol Ther. 2007 Feb;45(2):114-20. doi: 10.5414/cpp45114. Int J Clin Pharmacol Ther. 2007. PMID: 17323791 Clinical Trial.

7

Single- and multiple-dose pharmacokinetic, safety, and tolerability profiles of olanzapine long-acting injection: an open-label, multicenter, nonrandomized study in patients with schizophrenia.

Mitchell M, Kothare P, Bergstrom R, Zhao F, Jen KY, Walker D, Johnson J, McDonnell D. Mitchell M, et al. Clin Ther. 2013 Dec;35(12):1890-908. doi: 10.1016/j.clinthera.2013.09.023. Epub 2013 Oct 31. Clin Ther. 2013. PMID: 24184052 Clinical Trial.

8

Population PK Analyses of Ubrogepant (MK-1602), a CGRP Receptor Antagonist: Enriching In-Clinic Plasma PK Sampling With Outpatient Dried Blood Spot Sampling.

Li CC, Dockendorf M, Kowalski K, Yang B, Xu Y, Xie I, Kleijn HJ, Bosch R, Jones C, Thornton B, Marcantonio EE, Voss T, Bateman KP, Kothare PA. Li CC, et al. Among authors: kothare pa. J Clin Pharmacol. 2018 Mar;58(3):294-303. doi: 10.1002/jcph.1021. Epub 2017 Nov 14. J Clin Pharmacol. 2018. PMID: 29136283 Clinical Trial.

9

The pharmacokinetics and pharmacodynamics of prasugrel in healthy Chinese, Japanese, and Korean subjects compared with healthy Caucasian subjects.

Small DS, Kothare P, Yuen E, Lachno DR, Li YG, Winters KJ, Farid NA, Ni L, Jakubowski JA, Salazar DE, Thieu VT, Payne CD. Small DS, et al. Eur J Clin Pharmacol. 2010 Feb;66(2):127-35. doi: 10.1007/s00228-009-0737-1. Epub 2009 Nov 4. Eur J Clin Pharmacol. 2010. PMID: 19888568 Clinical Trial.

10

Pharmacokinetics and pharmacodynamics of exenatide extended-release after single and multiple dosing.

Fineman M, Flanagan S, Taylor K, Aisporna M, Shen LZ, Mace KF, Walsh B, Diamant M, Cirincione B, Kothare P, Li WI, MacConell L. Fineman M, et al. Clin Pharmacokinet. 2011 Jan;50(1):65-74. doi: 10.2165/11585880-000000000-00000. Clin Pharmacokinet. 2011. PMID: 21142268

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