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Chemically generated IgG2 bispecific antibodies through disulfide bridging.
Patterson JT, Gros E, Zhou H, Atassi G, Kerwin L, Carmody L, Zhu T, Jones B, Fu Y, Kaufmann GF. Patterson JT, et al. Among authors: kaufmann gf. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3647-3652. doi: 10.1016/j.bmcl.2017.07.021. Epub 2017 Jul 8. Bioorg Med Chem Lett. 2017. PMID: 28720505
PSMA-targeted bispecific Fab conjugates that engage T cells.
Patterson JT, Isaacson J, Kerwin L, Atassi G, Duggal R, Bresson D, Zhu T, Zhou H, Fu Y, Kaufmann GF. Patterson JT, et al. Among authors: kaufmann gf. Bioorg Med Chem Lett. 2017 Dec 15;27(24):5490-5495. doi: 10.1016/j.bmcl.2017.09.065. Epub 2017 Oct 6. Bioorg Med Chem Lett. 2017. PMID: 29126850
A Novel Affinity Engineered Anti-CD47 Antibody With Improved Therapeutic Index That Preserves Erythrocytes and Normal Immune Cells.
Thaker YR, Rivera I, Pedros C, Singh AR, Rivero-Nava L, Zhou H, Swanson BA, Kerwin L, Zhang Y, Gray JD, Kaufmann GF, Ji H, Allen RD, Bresson D. Thaker YR, et al. Among authors: kaufmann gf. Front Oncol. 2022 May 19;12:884196. doi: 10.3389/fonc.2022.884196. eCollection 2022. Front Oncol. 2022. PMID: 35664753 Free PMC article.
57 results