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Thiosemicarbazone derivatives, thiazolyl hydrazones, effectively inhibit leukemic tumor cell growth: Down-regulation of ribonucleotide reductase activity and synergism with arabinofuranosylcytosine.
Graser-Loescher G, Schoenhuber A, Ciglenec C, Eberl S, Krupitza G, Mader RM, Jadav SS, Jayaprakash V, Fritzer-Szekeres M, Szekeres T, Saiko P. Graser-Loescher G, et al. Among authors: krupitza g. Food Chem Toxicol. 2017 Oct;108(Pt A):53-62. doi: 10.1016/j.fct.2017.07.029. Epub 2017 Jul 14. Food Chem Toxicol. 2017. PMID: 28716444
Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside.
Grusch M, Polgar D, Gfatter S, Leuhuber K, Huettenbrenner S, Leisser C, Fuhrmann G, Kassie F, Steinkellner H, Smid K, Peters GJ, Jayaram HN, Klepal W, Szekeres T, Knasmüller S, Krupitza G. Grusch M, et al. Among authors: krupitza g. Cell Death Differ. 2002 Feb;9(2):169-78. doi: 10.1038/sj.cdd.4400937. Cell Death Differ. 2002. PMID: 11840167
Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells.
Fritzer-Szekeres M, Salamon A, Grusch M, Horvath Z, Höchtl T, Steinbrugger R, Jäger W, Krupitza G, Elford HL, Szekeres T. Fritzer-Szekeres M, et al. Among authors: krupitza g. Biochem Pharmacol. 2002 Aug 1;64(3):481-5. doi: 10.1016/s0006-2952(02)01186-3. Biochem Pharmacol. 2002. PMID: 12147300
142 results