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Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival.
Cosgrove CM, Cohn DE, Hampel H, Frankel WL, Jones D, McElroy JP, Suarez AA, Zhao W, Chen W, Salani R, Copeland LJ, O'Malley DM, Fowler JM, Yilmaz A, Chassen AS, Pearlman R, Goodfellow PJ, Backes FJ. Cosgrove CM, et al. Among authors: mcelroy jp. Gynecol Oncol. 2017 Sep;146(3):588-595. doi: 10.1016/j.ygyno.2017.07.003. Epub 2017 Jul 11. Gynecol Oncol. 2017. PMID: 28709704 Free PMC article.
Patterns of CTCF and ZFHX3 Mutation and Associated Outcomes in Endometrial Cancer.
Walker CJ, Miranda MA, O'Hern MJ, McElroy JP, Coombes KR, Bundschuh R, Cohn DE, Mutch DG, Goodfellow PJ. Walker CJ, et al. Among authors: mcelroy jp. J Natl Cancer Inst. 2015 Sep 1;107(11):djv249. doi: 10.1093/jnci/djv249. Print 2015 Nov. J Natl Cancer Inst. 2015. PMID: 26330387 Free PMC article.
Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide: An Analysis From the NRG Oncology/RTOG 0424 Trial.
Bell EH, Zhang P, Fisher BJ, Macdonald DR, McElroy JP, Lesser GJ, Fleming J, Chakraborty AR, Liu Z, Becker AP, Fabian D, Aldape KD, Ashby LS, Werner-Wasik M, Walker EM, Bahary JP, Kwok Y, Yu HM, Laack NN, Schultz CJ, Gray HJ, Robins HI, Mehta MP, Chakravarti A. Bell EH, et al. Among authors: mcelroy jp. JAMA Oncol. 2018 Oct 1;4(10):1405-1409. doi: 10.1001/jamaoncol.2018.1977. JAMA Oncol. 2018. PMID: 29955793 Free PMC article. Clinical Trial.
Double somatic mismatch repair gene pathogenic variants as common as Lynch syndrome among endometrial cancer patients.
Hampel H, Pearlman R, de la Chapelle A, Pritchard CC, Zhao W, Jones D, Yilmaz A, Chen W, Frankel WL, Suarez AA, Cosgrove C, Backes F, Copeland L, Fowler J, O'Malley D, Salani R, McElroy JP, Stanich PP, Goodfellow P, Cohn DE. Hampel H, et al. Among authors: mcelroy jp. Gynecol Oncol. 2021 Jan;160(1):161-168. doi: 10.1016/j.ygyno.2020.10.012. Epub 2020 Oct 21. Gynecol Oncol. 2021. PMID: 33393477 Free PMC article.
Up-Front Multigene Panel Testing for Cancer Susceptibility in Patients With Newly Diagnosed Endometrial Cancer: A Multicenter Prospective Study.
Levine MD, Pearlman R, Hampel H, Cosgrove C, Cohn D, Chassen A, Suarez A, Barrington DA, McElroy JP, Waggoner S, Nakayama J, Billingsley C, Resnick K, Andrews S, Singh S, Jenison E, Clements A, Neff R, Goodfellow PJ; Ohio Prevention and Treatment of Endometrial Cancer Initiative Study Group. Levine MD, et al. Among authors: mcelroy jp. JCO Precis Oncol. 2021 Nov;5:1588-1602. doi: 10.1200/PO.21.00249. JCO Precis Oncol. 2021. PMID: 34994648 Free PMC article.
Differences in somatic TP53 mutation type in breast tumors by race and receptor status.
Pollock NC, Ramroop JR, Hampel H, Troester MA, Conway K, Hu JJ, Freudenheim JL, Olopade OI, Huo D, Ziv E, Neuhausen SL, Stevens P, McElroy JP, Toland AE. Pollock NC, et al. Among authors: mcelroy jp. Breast Cancer Res Treat. 2022 Apr;192(3):639-648. doi: 10.1007/s10549-022-06509-3. Epub 2022 Mar 14. Breast Cancer Res Treat. 2022. PMID: 35286522 Free PMC article.
Association of ESR1 germline variants with TP53 somatic variants in breast tumors in a genome-wide study.
Tjader NP, Beer AJ, Ramroop J, Tai MC, Ping J, Gandhi T, Dauch C, Neuhausen SL, Ziv E, Sotelo N, Ghanekar S, Meadows O, Paredes M, Gillespie J, Aeilts A, Hampel H, Zheng W, Jia G, Hu Q, Wei L, Liu S, Ambrosone CB, Palmer JR, Carpten JD, Yao S, Stevens P, Ho WK, Pan JW, Fadda P, Huo D, Teo SH, McElroy JP, Toland AE. Tjader NP, et al. Among authors: mcelroy jp. medRxiv [Preprint]. 2023 Dec 6:2023.12.06.23299442. doi: 10.1101/2023.12.06.23299442. medRxiv. 2023. Update in: Cancer Res Commun. 2024 Jun 27;4(6):1597-1608. doi: 10.1158/2767-9764.CRC-24-0026 PMID: 38106140 Free PMC article. Updated. Preprint.
Association of ESR1 Germline Variants with TP53 Somatic Variants in Breast Tumors in a Genome-wide Study.
Tjader NP, Beer AJ, Ramroop J, Tai MC, Ping J, Gandhi T, Dauch C, Neuhausen SL, Ziv E, Sotelo N, Ghanekar S, Meadows O, Paredes M, Gillespie JL, Aeilts AM, Hampel H, Zheng W, Jia G, Hu Q, Wei L, Liu S, Ambrosone CB, Palmer JR, Carpten JD, Yao S, Stevens P, Ho WK, Pan JW, Fadda P, Huo D, Teo SH, McElroy JP, Toland AE. Tjader NP, et al. Among authors: mcelroy jp. Cancer Res Commun. 2024 Jun 27;4(6):1597-1608. doi: 10.1158/2767-9764.CRC-24-0026. Cancer Res Commun. 2024. PMID: 38836758 Free PMC article.
Molecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525.
Bell EH, Pugh SL, McElroy JP, Gilbert MR, Mehta M, Klimowicz AC, Magliocco A, Bredel M, Robe P, Grosu AL, Stupp R, Curran W Jr, Becker AP, Salavaggione AL, Barnholtz-Sloan JS, Aldape K, Blumenthal DT, Brown PD, Glass J, Souhami L, Lee RJ, Brachman D, Flickinger J, Won M, Chakravarti A. Bell EH, et al. Among authors: mcelroy jp. JAMA Oncol. 2017 Jun 1;3(6):784-792. doi: 10.1001/jamaoncol.2016.6020. JAMA Oncol. 2017. PMID: 28097324 Free PMC article. Clinical Trial.
73 results