Quan J - Search Results

1

Synthesis and Evaluation of Diphenyl Conjugated Imidazole Derivatives as Potential Glutaminyl Cyclase Inhibitors for Treatment of Alzheimer's Disease.

Li M, Dong Y, Yu X, Li Y, Zou Y, Zheng Y, He Z, Liu Z, Quan J, Bu X, Wu H. Li M, et al. Among authors: quan j. J Med Chem. 2017 Aug 10;60(15):6664-6677. doi: 10.1021/acs.jmedchem.7b00648. Epub 2017 Jul 25. J Med Chem. 2017. PMID: 28700245

2

Benzo[e]isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode.

Zou H, Zhou L, Li Y, Cui Y, Zhong H, Pan Z, Yang Z, Quan J. Zou H, et al. Among authors: quan j. J Med Chem. 2010 Feb 11;53(3):994-1003. doi: 10.1021/jm9013373. J Med Chem. 2010. PMID: 20030405

3

Structure-based design of benzo[e]isoindole-1,3-dione derivatives as selective GSK-3β inhibitors to activate Wnt/β-catenin pathway.

Yue H, Lu F, Shen C, Quan JM. Yue H, et al. Bioorg Chem. 2015 Aug;61:21-7. doi: 10.1016/j.bioorg.2015.05.009. Epub 2015 May 29. Bioorg Chem. 2015. PMID: 26057861

4

Distinct tubulin dynamics in cancer cells explored using a highly tubulin-specific fluorescent probe.

Zhu C, Zuo Y, Liang B, Yue H, Yue X, Wen G, Wang R, Quan J, Du J, Bu X. Zhu C, et al. Among authors: quan j. Chem Commun (Camb). 2015 Sep 7;51(69):13400-3. doi: 10.1039/c5cc04927j. Epub 2015 Jul 27. Chem Commun (Camb). 2015. PMID: 26214302

5

Mitochondria-Targeted Approach: Remarkably Enhanced Cellular Bioactivities of TPP2a as Selective Inhibitor and Probe toward TrxR.

Liang B, Shao W, Zhu C, Wen G, Yue X, Wang R, Quan J, Du J, Bu X. Liang B, et al. Among authors: quan j. ACS Chem Biol. 2016 Feb 19;11(2):425-34. doi: 10.1021/acschembio.5b00708. Epub 2015 Dec 14. ACS Chem Biol. 2016. PMID: 26653078

6

Inhibitory effect of flavonoids on human glutaminyl cyclase.

Li M, Dong Y, Yu X, Zou Y, Zheng Y, Bu X, Quan J, He Z, Wu H. Li M, et al. Among authors: quan j. Bioorg Med Chem. 2016 May 15;24(10):2280-6. doi: 10.1016/j.bmc.2016.03.064. Epub 2016 Apr 1. Bioorg Med Chem. 2016. PMID: 27061673

7

Stabilizing amyloid-β peptide by the N-terminus capture is capable of preventing and eliminating amyloid-β oligomers.

Wen G, Chen D, Qin W, Zhou B, Wang Y, Liu Z, Du J, Zhou Q, Quan J, Bu X. Wen G, et al. Among authors: quan j. Chem Commun (Camb). 2017 Jul 4;53(54):7673-7676. doi: 10.1039/c7cc03102e. Chem Commun (Camb). 2017. PMID: 28644501

8

Dissociation of haemolytic and oligomer-preventing activities of gramicidin S derivatives targeting the amyloid-β N-terminus.

Chen D, Qin W, Wen G, Shi B, Liu Z, Wang Y, Zhou Q, Quan J, Zhou B, Bu X. Chen D, et al. Among authors: quan j. Chem Commun (Camb). 2017 Dec 14;53(100):13340-13343. doi: 10.1039/c7cc08180d. Chem Commun (Camb). 2017. PMID: 29188836

9

Blockade of USP14 potentiates type I interferon signaling and radiation-induced antitumor immunity via preventing IRF3 deubiquitination.

Wu W, Xu H, Liao C, Wang Y, Wu R, Wu J, Zheng W, Li Y, Jin C, Zhao Y, Quan J, Yue X, Bu X. Wu W, et al. Among authors: quan j. Cell Oncol (Dordr). 2022 Dec;45(6):1347-1361. doi: 10.1007/s13402-022-00724-2. Epub 2022 Oct 7. Cell Oncol (Dordr). 2022. PMID: 36205846

10

Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation.

Wang X, Wang Y, Cao A, Luo Q, Chen D, Zhao W, Xu J, Li Q, Bu X, Quan J. Wang X, et al. Among authors: quan j. Nat Commun. 2023 Oct 2;14(1):6132. doi: 10.1038/s41467-023-41892-5. Nat Commun. 2023. PMID: 37783727 Free PMC article.

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