Krumpe LRH - Search Results

1

Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1).

Bermingham A, Price E, Marchand C, Chergui A, Naumova A, Whitson EL, Krumpe LRH, Goncharova EI, Evans JR, McKee TC, Henrich CJ, Pommier Y, O'Keefe BR. Bermingham A, et al. Among authors: krumpe lrh. SLAS Discov. 2017 Oct;22(9):1093-1105. doi: 10.1177/2472555217717200. Epub 2017 Jul 11. SLAS Discov. 2017. PMID: 28697309 Free PMC article.

2

Atomic-resolution crystal structure of the antiviral lectin scytovirin.

Moulaei T, Botos I, Ziółkowska NE, Bokesch HR, Krumpe LR, McKee TC, O'Keefe BR, Dauter Z, Wlodawer A. Moulaei T, et al. Protein Sci. 2007 Dec;16(12):2756-60. doi: 10.1110/ps.073157507. Epub 2007 Oct 26. Protein Sci. 2007. PMID: 17965185 Free PMC article.

3

Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays.

Sztuba-Solinska J, Shenoy SR, Gareiss P, Krumpe LR, Le Grice SF, O'Keefe BR, Schneekloth JS Jr. Sztuba-Solinska J, et al. J Am Chem Soc. 2014 Jun 11;136(23):8402-10. doi: 10.1021/ja502754f. Epub 2014 May 28. J Am Chem Soc. 2014. PMID: 24820959 Free PMC article.

4

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus.

Garrison AR, Giomarelli BG, Lear-Rooney CM, Saucedo CJ, Yellayi S, Krumpe LR, Rose M, Paragas J, Bray M, Olinger GG Jr, McMahon JB, Huggins J, O'Keefe BR. Garrison AR, et al. Antiviral Res. 2014 Dec;112:1-7. doi: 10.1016/j.antiviral.2014.09.012. Epub 2014 Oct 5. Antiviral Res. 2014. PMID: 25265598 Free PMC article.

5

Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus.

Moulaei T, Alexandre KB, Shenoy SR, Meyerson JR, Krumpe LR, Constantine B, Wilson J, Buckheit RW Jr, McMahon JB, Subramaniam S, Wlodawer A, O'Keefe BR. Moulaei T, et al. Retrovirology. 2015 Jan 23;12:6. doi: 10.1186/s12977-014-0127-3. Retrovirology. 2015. PMID: 25613831 Free PMC article.

6

Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro.

Vamvaka E, Evans A, Ramessar K, Krumpe LR, Shattock RJ, O'Keefe BR, Christou P, Capell T. Vamvaka E, et al. Plant Cell Rep. 2016 Jun;35(6):1309-19. doi: 10.1007/s00299-016-1963-5. Epub 2016 Mar 23. Plant Cell Rep. 2016. PMID: 27007716 Free PMC article.

7

A Designed "Nested" Dimer of Cyanovirin-N Increases Antiviral Activity.

Woodrum BW, Maxwell J, Allen DM, Wilson J, Krumpe LR, Bobkov AA, Hill RB, Kibler KV, O'Keefe BR, Ghirlanda G. Woodrum BW, et al. Viruses. 2016 Jun 6;8(6):158. doi: 10.3390/v8060158. Viruses. 2016. PMID: 27275831 Free PMC article.

8

Secondary Metabolites from the Fungus Dictyosporium sp. and Their MALT1 Inhibitory Activities.

Tran TD, Wilson BAP, Henrich CJ, Staudt LM, Krumpe LRH, Smith EA, King J, Wendt KL, Stchigel AM, Miller AN, Cichewicz RH, O'Keefe BR, Gustafson KR. Tran TD, et al. Among authors: krumpe lrh. J Nat Prod. 2019 Jan 25;82(1):154-162. doi: 10.1021/acs.jnatprod.8b00871. Epub 2019 Jan 2. J Nat Prod. 2019. PMID: 30600998 Free PMC article.

9

The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation.

Matarlo JS, Krumpe LRH, Heinz WF, Oh D, Shenoy SR, Thomas CL, Goncharova EI, Lockett SJ, O'Keefe BR. Matarlo JS, et al. Among authors: krumpe lrh. Cell Chem Biol. 2019 Aug 15;26(8):1133-1142.e4. doi: 10.1016/j.chembiol.2019.04.011. Epub 2019 May 30. Cell Chem Biol. 2019. PMID: 31155509 Free PMC article.

10

Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge.

Lo MK, Spengler JR, Krumpe LRH, Welch SR, Chattopadhyay A, Harmon JR, Coleman-McCray JD, Scholte FEM, Hotard AL, Fuqua JL, Rose JK, Nichol ST, Palmer KE, O'Keefe BR, Spiropoulou CF. Lo MK, et al. Among authors: krumpe lrh. J Infect Dis. 2020 May 11;221(Supplement_4):S480-S492. doi: 10.1093/infdis/jiz630. J Infect Dis. 2020. PMID: 32037447 Free PMC article.

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