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Zn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria.
Sci Rep. 2017 Jul 7;7(1):4893. doi: 10.1038/s41598-017-04868-2.
Sci Rep. 2017.
PMID: 28687742
Free PMC article.
The frontline antibiotic vancomycin induces a zinc starvation response in bacteria by binding to Zn(II).
Zarkan A, Macklyne HR, Truman AW, Hesketh AR, Hong HJ.
Zarkan A, et al. Among authors: macklyne hr.
Sci Rep. 2016 Jan 22;6:19602. doi: 10.1038/srep19602.
Sci Rep. 2016.
PMID: 26797186
Free PMC article.
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