Hansen HH - Search Results

1

Mouse models of nonalcoholic steatohepatitis in preclinical drug development.

Hansen HH, Feigh M, Veidal SS, Rigbolt KT, Vrang N, Fosgerau K. Hansen HH, et al. Drug Discov Today. 2017 Nov;22(11):1707-1718. doi: 10.1016/j.drudis.2017.06.007. Epub 2017 Jul 4. Drug Discov Today. 2017. PMID: 28687459 Free article. Review.

2

The sodium glucose cotransporter type 2 inhibitor empagliflozin preserves β-cell mass and restores glucose homeostasis in the male zucker diabetic fatty rat.

Hansen HH, Jelsing J, Hansen CF, Hansen G, Vrang N, Mark M, Klein T, Mayoux E. Hansen HH, et al. Among authors: hansen g, hansen cf. J Pharmacol Exp Ther. 2014 Sep;350(3):657-64. doi: 10.1124/jpet.114.213454. Epub 2014 Jul 3. J Pharmacol Exp Ther. 2014. PMID: 24993361

3

The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the diet-induced obese rat.

Hansen HH, Hansen G, Paulsen S, Vrang N, Mark M, Jelsing J, Klein T. Hansen HH, et al. Among authors: hansen g. Eur J Pharmacol. 2014 Oct 15;741:254-63. doi: 10.1016/j.ejphar.2014.08.010. Epub 2014 Aug 24. Eur J Pharmacol. 2014. PMID: 25160746

4

The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer's Disease.

Hansen HH, Fabricius K, Barkholt P, Niehoff ML, Morley JE, Jelsing J, Pyke C, Knudsen LB, Farr SA, Vrang N. Hansen HH, et al. J Alzheimers Dis. 2015;46(4):877-88. doi: 10.3233/JAD-143090. J Alzheimers Dis. 2015. PMID: 25869785 Free PMC article.

5

The GLP-1 receptor agonist liraglutide reduces pathology-specific tau phosphorylation and improves motor function in a transgenic hTauP301L mouse model of tauopathy.

Hansen HH, Barkholt P, Fabricius K, Jelsing J, Terwel D, Pyke C, Knudsen LB, Vrang N. Hansen HH, et al. Brain Res. 2016 Mar 1;1634:158-170. doi: 10.1016/j.brainres.2015.12.052. Epub 2015 Dec 31. Brain Res. 2016. PMID: 26746341

6

Alterations in hypothalamic gene expression following Roux-en-Y gastric bypass.

Barkholt P, Pedersen PJ, Hay-Schmidt A, Jelsing J, Hansen HH, Vrang N. Barkholt P, et al. Among authors: hansen hh. Mol Metab. 2016 Jan 25;5(4):296-304. doi: 10.1016/j.molmet.2016.01.006. eCollection 2016 Apr. Mol Metab. 2016. PMID: 27069869 Free PMC article.

7

Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease.

Hansen HH, Fabricius K, Barkholt P, Mikkelsen JD, Jelsing J, Pyke C, Knudsen LB, Vrang N. Hansen HH, et al. Brain Res. 2016 Sep 1;1646:354-365. doi: 10.1016/j.brainres.2016.05.038. Epub 2016 May 24. Brain Res. 2016. PMID: 27233809

8

Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.

Hansen HH, Fabricius K, Barkholt P, Kongsbak-Wismann P, Schlumberger C, Jelsing J, Terwel D, Termont A, Pyke C, Knudsen LB, Vrang N. Hansen HH, et al. PLoS One. 2016 Jul 15;11(7):e0158205. doi: 10.1371/journal.pone.0158205. eCollection 2016. PLoS One. 2016. PMID: 27421117 Free PMC article.

9

Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control.

Fernandez-Cachon ML, Pedersen SL, Rigbolt KT, Zhang C, Fabricius K, Hansen HH, Elster L, Fink LN, Schäfer M, Rhee NA, Langholz E, Wandall E, Friis SU, Vilmann P, Kristiansen VB, Schmidt C, Schreiter K, Breitschopf K, Hübschle T, Jorsal T, Vilsbøll T, Schmidt T, Theis S, Knop FK, Larsen PJ, Jelsing J. Fernandez-Cachon ML, et al. Among authors: hansen hh. Peptides. 2018 Mar;101:32-43. doi: 10.1016/j.peptides.2017.12.024. Epub 2017 Dec 28. Peptides. 2018. PMID: 29289697 Clinical Trial.

10

Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis.

Tølbøl KS, Kristiansen MN, Hansen HH, Veidal SS, Rigbolt KT, Gillum MP, Jelsing J, Vrang N, Feigh M. Tølbøl KS, et al. Among authors: hansen hh. World J Gastroenterol. 2018 Jan 14;24(2):179-194. doi: 10.3748/wjg.v24.i2.179. World J Gastroenterol. 2018. PMID: 29375204 Free PMC article.

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