Laffan MA - Search Results

1

Expanded repertoire of RASGRP2 variants responsible for platelet dysfunction and severe bleeding.

Westbury SK, Canault M, Greene D, Bermejo E, Hanlon K, Lambert MP, Millar CM, Nurden P, Obaji SG, Revel-Vilk S, Van Geet C, Downes K, Papadia S, Tuna S, Watt C; NIHR BioResource–Rare Diseases Consortium; Freson K, Laffan MA, Ouwehand WH, Alessi MC, Turro E, Mumford AD. Westbury SK, et al. Among authors: laffan ma. Blood. 2017 Aug 24;130(8):1026-1030. doi: 10.1182/blood-2017-03-776773. Epub 2017 Jun 21. Blood. 2017. PMID: 28637664 Free PMC article.

2

Elevation of FVIII: C in venous thromboembolism is persistent and independent of the acute phase response.

O'Donnell J, Mumford AD, Manning RA, Laffan M. O'Donnell J, et al. Thromb Haemost. 2000 Jan;83(1):10-3. Thromb Haemost. 2000. PMID: 10669146

3

Fibrinogen Bbeta14 Arg-->Cys: further evidence for a role in thrombosis.

Vakalopoulou S, Mille-Baker B, Mumford A, Manning R, Laffan M. Vakalopoulou S, et al. Blood Coagul Fibrinolysis. 1999 Oct;10(7):403-8. Blood Coagul Fibrinolysis. 1999. PMID: 10695765

4

Bleeding symptoms and coagulation abnormalities in 337 patients with AL-amyloidosis.

Mumford AD, O'Donnell J, Gillmore JD, Manning RA, Hawkins PN, Laffan M. Mumford AD, et al. Br J Haematol. 2000 Aug;110(2):454-60. doi: 10.1046/j.1365-2141.2000.02183.x. Br J Haematol. 2000. PMID: 10971408 Free article.

5

Marked elevation of thrombin generation in patients with elevated FVIII:C and venous thromboembolism.

O'Donnell J, Mumford AD, Manning RA, Laffan MA. O'Donnell J, et al. Among authors: laffan ma. Br J Haematol. 2001 Dec;115(3):687-91. doi: 10.1046/j.1365-2141.2001.03146.x. Br J Haematol. 2001. PMID: 11736955 Free article.

6

A Tyr346-->Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII:C assay discrepancy.

Mumford AD, Laffan M, O'Donnell J, McVey JH, Johnson DJ, Manning RA, Kemball-Cook G. Mumford AD, et al. Br J Haematol. 2002 Aug;118(2):589-94. doi: 10.1046/j.1365-2141.2002.03617.x. Br J Haematol. 2002. PMID: 12139751 Free article.

7

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia.

Ghevaert C, Salsmann A, Watkins NA, Schaffner-Reckinger E, Rankin A, Garner SF, Stephens J, Smith GA, Debili N, Vainchenker W, de Groot PG, Huntington JA, Laffan M, Kieffer N, Ouwehand WH. Ghevaert C, et al. Blood. 2008 Apr 1;111(7):3407-14. doi: 10.1182/blood-2007-09-112615. Epub 2007 Dec 7. Blood. 2008. PMID: 18065693 Free article.

8

Characterization of W1745C and S1783A: 2 novel mutations causing defective collagen binding in the A3 domain of von Willebrand factor.

Riddell AF, Gomez K, Millar CM, Mellars G, Gill S, Brown SA, Sutherland M, Laffan MA, McKinnon TA. Riddell AF, et al. Among authors: laffan ma. Blood. 2009 Oct 15;114(16):3489-96. doi: 10.1182/blood-2008-10-184317. Epub 2009 Aug 17. Blood. 2009. PMID: 19687512 Free article.

9

Endothelial von Willebrand factor regulates angiogenesis.

Starke RD, Ferraro F, Paschalaki KE, Dryden NH, McKinnon TA, Sutton RE, Payne EM, Haskard DO, Hughes AD, Cutler DF, Laffan MA, Randi AM. Starke RD, et al. Among authors: laffan ma. Blood. 2011 Jan 20;117(3):1071-80. doi: 10.1182/blood-2010-01-264507. Epub 2010 Nov 3. Blood. 2011. PMID: 21048155 Free PMC article.

10

Pregnancy in type 2B VWD: a case series.

Ranger A, Manning RA, Lyall H, Laffan MA, Millar CM. Ranger A, et al. Among authors: laffan ma. Haemophilia. 2012 May;18(3):406-12. doi: 10.1111/j.1365-2516.2011.02691.x. Epub 2011 Nov 14. Haemophilia. 2012. PMID: 22077376

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