Xu CF - Search Results

1

Discovery and Characterization of Histidine Oxidation Initiated Cross-links in an IgG1 Monoclonal Antibody.

Xu CF, Chen Y, Yi L, Brantley T, Stanley B, Sosic Z, Zang L. Xu CF, et al. Anal Chem. 2017 Aug 1;89(15):7915-7923. doi: 10.1021/acs.analchem.7b00860. Epub 2017 Jul 10. Anal Chem. 2017. PMID: 28635253

2

Size-exclusion chromatography-mass spectrometry with m-nitrobenzyl alcohol as post-column additive for direct characterization of size variants of monoclonal antibodies.

Xu CF, Zang L, Weiskopf A. Xu CF, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 1;960:230-8. doi: 10.1016/j.jchromb.2014.04.023. Epub 2014 Apr 21. J Chromatogr B Analyt Technol Biomed Life Sci. 2014. PMID: 24835510

3

Effect of protein aggregates on characterization of FcRn binding of Fc-fusion therapeutics.

Bajardi-Taccioli A, Blum A, Xu C, Sosic Z, Bergelson S, Feschenko M. Bajardi-Taccioli A, et al. Mol Immunol. 2015 Oct;67(2 Pt B):616-24. doi: 10.1016/j.molimm.2015.06.031. Epub 2015 Aug 5. Mol Immunol. 2015. PMID: 26254986

4

Application of a label-free and domain-specific free thiol method in monoclonal antibody characterization.

Pu Y, Chen Y, Nguyen T, Xu CF, Zang L, Sosic Z, Carlage T. Pu Y, et al. Among authors: xu cf. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 May 1;1114-1115:93-99. doi: 10.1016/j.jchromb.2019.03.032. Epub 2019 Mar 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 30939413 Free article.

5

Sequence Variant and Posttranslational Modification Analysis During Cell Line Selection via High-Throughput Peptide Mapping.

Xu CF, Wang Y, Bryngelson P, Sosic Z, Zang L. Xu CF, et al. Adv Exp Med Biol. 2019;1140:225-236. doi: 10.1007/978-3-030-15950-4_12. Adv Exp Med Biol. 2019. PMID: 31347050

6

Biolayer Interferometry-based FcγRIIa binding assay for a therapeutic antibody with strong effector function.

Bajardi-Taccioli A, Co C, Bond C, Masci A, Brantley T, Xu C, Bergelson S, Feschenko M. Bajardi-Taccioli A, et al. Anal Biochem. 2020 Dec 15;611:113842. doi: 10.1016/j.ab.2020.113842. Epub 2020 Aug 2. Anal Biochem. 2020. PMID: 32755599

7

A Highly Sensitive LC-MS/MS Method for Targeted Quantitation of Lipase Host Cell Proteins in Biotherapeutics.

Chen Y, Xu CF, Stanley B, Evangelist G, Brinkmann A, Liu S, McCarthy S, Xiong L, Jones E, Sosic Z, Yeung B. Chen Y, et al. Among authors: xu cf. J Pharm Sci. 2021 Dec;110(12):3811-3818. doi: 10.1016/j.xphs.2021.08.024. Epub 2021 Aug 28. J Pharm Sci. 2021. PMID: 34461112 Free article.

8

Evaluation of the impact of antibody fragments on aggregation of intact molecules via size exclusion chromatography coupled with native mass spectrometry.

Xu J, Coughlin JE, Szyjka M, Jabary S, Saluja S, Sosic Z, Chen Y, Xu CF. Xu J, et al. Among authors: xu cf. MAbs. 2024 Jan-Dec;16(1):2334783. doi: 10.1080/19420862.2024.2334783. Epub 2024 Mar 27. MAbs. 2024. PMID: 38536719 Free PMC article.

9

Genetic mutation analysis at early stages of cell line development using next generation sequencing.

Wright C, Groot J, Swahn S, McLaughlin H, Liu M, Xu C, Sun C, Zheng E, Estes S. Wright C, et al. Biotechnol Prog. 2016 May;32(3):813-7. doi: 10.1002/btpr.2263. Epub 2016 Apr 14. Biotechnol Prog. 2016. PMID: 27004436

10

Benchmarking and optimization of a high-throughput sequencing based method for transgene sequence variant analysis in biotherapeutic cell line development.

Groot J, Zhou Y, Marshall E, Cullen P, Carlile T, Lin D, Xu CF, Crisafulli J, Sun C, Casey F, Zhang B, Alves C. Groot J, et al. Among authors: xu cf. Biotechnol J. 2021 Aug;16(8):e2000548. doi: 10.1002/biot.202000548. Epub 2021 Jun 3. Biotechnol J. 2021. PMID: 34018310

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