Tate EW - Search Results

1

Structure-guided optimization of quinoline inhibitors of Plasmodium N-myristoyltransferase.

Goncalves V, Brannigan JA, Laporte A, Bell AS, Roberts SM, Wilkinson AJ, Leatherbarrow RJ, Tate EW. Goncalves V, et al. Among authors: tate ew. Medchemcomm. 2017 Jan 1;8(1):191-197. doi: 10.1039/c6md00531d. Epub 2016 Nov 11. Medchemcomm. 2017. PMID: 28626547 Free PMC article.

2

Total synthesis of the macrocyclic cysteine knot microprotein MCoTI-II.

Thongyoo P, Tate EW, Leatherbarrow RJ. Thongyoo P, et al. Among authors: tate ew. Chem Commun (Camb). 2006 Jul 21;(27):2848-50. doi: 10.1039/b607324g. Chem Commun (Camb). 2006. PMID: 17007393

3

Immobilized protease-assisted synthesis of engineered cysteine-knot microproteins.

Thongyoo P, Jaulent AM, Tate EW, Leatherbarrow RJ. Thongyoo P, et al. Among authors: tate ew. Chembiochem. 2007 Jul 9;8(10):1107-9. doi: 10.1002/cbic.200700187. Chembiochem. 2007. PMID: 17526063 No abstract available.

4

Molecules incorporating a benzothiazole core scaffold inhibit the N-myristoyltransferase of Plasmodium falciparum.

Bowyer PW, Gunaratne RS, Grainger M, Withers-Martinez C, Wickramsinghe SR, Tate EW, Leatherbarrow RJ, Brown KA, Holder AA, Smith DF. Bowyer PW, et al. Among authors: tate ew. Biochem J. 2007 Dec 1;408(2):173-80. doi: 10.1042/BJ20070692. Biochem J. 2007. PMID: 17714074 Free PMC article.

5

Site-specific N-terminal labelling of proteins in vitro and in vivo using N-myristoyl transferase and bioorthogonal ligation chemistry.

Heal WP, Wickramasinghe SR, Bowyer PW, Holder AA, Smith DF, Leatherbarrow RJ, Tate EW. Heal WP, et al. Among authors: tate ew. Chem Commun (Camb). 2008 Jan 28;(4):480-2. doi: 10.1039/b716115h. Epub 2007 Nov 13. Chem Commun (Camb). 2008. PMID: 18188474

6

N-myristoyltransferase: a prospective drug target for protozoan parasites.

Bowyer PW, Tate EW, Leatherbarrow RJ, Holder AA, Smith DF, Brown KA. Bowyer PW, et al. Among authors: tate ew. ChemMedChem. 2008 Mar;3(3):402-8. doi: 10.1002/cmdc.200700301. ChemMedChem. 2008. PMID: 18324715 Review. No abstract available.

7

Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides.

Thongyoo P, Roqué-Rosell N, Leatherbarrow RJ, Tate EW. Thongyoo P, et al. Among authors: tate ew. Org Biomol Chem. 2008 Apr 21;6(8):1462-70. doi: 10.1039/b801667d. Epub 2008 Mar 6. Org Biomol Chem. 2008. PMID: 18385853 Free article.

8

N-Myristoyl transferase-mediated protein labelling in vivo.

Heal WP, Wickramasinghe SR, Leatherbarrow RJ, Tate EW. Heal WP, et al. Among authors: tate ew. Org Biomol Chem. 2008 Jul 7;6(13):2308-15. doi: 10.1039/b803258k. Epub 2008 May 12. Org Biomol Chem. 2008. PMID: 18563263 Free article.

9

Specific N-terminal protein labelling: use of FMDV 3C pro protease and native chemical ligation.

Busch GK, Tate EW, Gaffney PR, Rosivatz E, Woscholski R, Leatherbarrow RJ. Busch GK, et al. Among authors: tate ew. Chem Commun (Camb). 2008 Aug 7;(29):3369-71. doi: 10.1039/b806727a. Epub 2008 Jun 25. Chem Commun (Camb). 2008. PMID: 18633492

10

Potent inhibitors of beta-tryptase and human leukocyte elastase based on the MCoTI-II scaffold.

Thongyoo P, Bonomelli C, Leatherbarrow RJ, Tate EW. Thongyoo P, et al. Among authors: tate ew. J Med Chem. 2009 Oct 22;52(20):6197-200. doi: 10.1021/jm901233u. J Med Chem. 2009. PMID: 19772295

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