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Page 1
Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.
Tanaka T, Takahashi K, Yamane M, Tomida S, Nakamura S, Oshima K, Niwa A, Nishikomori R, Kambe N, Hara H, Mitsuyama M, Morone N, Heuser JE, Yamamoto T, Watanabe A, Sato-Otsubo A, Ogawa S, Asaka I, Heike T, Yamanaka S, Nakahata T, Saito MK. Tanaka T, et al. Blood. 2012 Aug 9;120(6):1299-308. doi: 10.1182/blood-2012-03-417881. Epub 2012 Jun 21. Blood. 2012. PMID: 22723549 Free article.
Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway.
Yokoyama K, Ikeya M, Umeda K, Oda H, Nodomi S, Nasu A, Matsumoto Y, Izawa K, Horigome K, Kusaka T, Tanaka T, Saito MK, Yasumi T, Nishikomori R, Ohara O, Nakayama N, Nakahata T, Heike T, Toguchida J. Yokoyama K, et al. Among authors: tanaka t. Arthritis Rheumatol. 2015 Jan;67(1):302-14. doi: 10.1002/art.38912. Arthritis Rheumatol. 2015. PMID: 25302486
Identification of a High-Frequency Somatic NLRC4 Mutation as a Cause of Autoinflammation by Pluripotent Cell-Based Phenotype Dissection.
Kawasaki Y, Oda H, Ito J, Niwa A, Tanaka T, Hijikata A, Seki R, Nagahashi A, Osawa M, Asaka I, Watanabe A, Nishimata S, Shirai T, Kawashima H, Ohara O, Nakahata T, Nishikomori R, Heike T, Saito MK. Kawasaki Y, et al. Among authors: tanaka t. Arthritis Rheumatol. 2017 Feb;69(2):447-459. doi: 10.1002/art.39960. Arthritis Rheumatol. 2017. PMID: 27788288
Tricho-hepato-enteric syndrome with novel SKIV2L gene mutations: A case report.
Hiejima E, Yasumi T, Nakase H, Matsuura M, Honzawa Y, Higuchi H, Okafuji I, Yorifuji T, Tanaka T, Izawa K, Kawai T, Nishikomori R, Heike T. Hiejima E, et al. Among authors: tanaka t. Medicine (Baltimore). 2017 Nov;96(46):e8601. doi: 10.1097/MD.0000000000008601. Medicine (Baltimore). 2017. PMID: 29145277 Free PMC article.
National survey of Japanese patients with mevalonate kinase deficiency reveals distinctive genetic and clinical characteristics.
Tanaka T, Yoshioka K, Nishikomori R, Sakai H, Abe J, Yamashita Y, Hiramoto R, Morimoto A, Ishii E, Arakawa H, Kaneko U, Ohshima Y, Okamoto N, Ohara O, Hata I, Shigematsu Y, Kawai T, Yasumi T, Heike T. Tanaka T, et al. Mod Rheumatol. 2019 Jan;29(1):181-187. doi: 10.1080/14397595.2018.1442639. Epub 2018 Mar 2. Mod Rheumatol. 2019. PMID: 29451047
Rescue of recurrent deep intronic mutation underlying cell type-dependent quantitative NEMO deficiency.
Boisson B, Honda Y, Ajiro M, Bustamante J, Bendavid M, Gennery AR, Kawasaki Y, Ichishima J, Osawa M, Nihira H, Shiba T, Tanaka T, Chrabieh M, Bigio B, Hur H, Itan Y, Liang Y, Okada S, Izawa K, Nishikomori R, Ohara O, Heike T, Abel L, Puel A, Saito MK, Casanova JL, Hagiwara M, Yasumi T. Boisson B, et al. Among authors: tanaka t. J Clin Invest. 2019 Feb 1;129(2):583-597. doi: 10.1172/JCI124011. Epub 2018 Dec 18. J Clin Invest. 2019. PMID: 30422821 Free PMC article.
Functional evaluation of the pathological significance of MEFV variants using induced pluripotent stem cell-derived macrophages.
Shiba T, Tanaka T, Ida H, Watanabe M, Nakaseko H, Osawa M, Shibata H, Izawa K, Yasumi T, Kawasaki Y, Saito MK, Takita J, Heike T, Nishikomori R. Shiba T, et al. Among authors: tanaka t. J Allergy Clin Immunol. 2019 Nov;144(5):1438-1441.e12. doi: 10.1016/j.jaci.2019.07.039. Epub 2019 Sep 18. J Allergy Clin Immunol. 2019. PMID: 31542286 No abstract available.
Pluripotent stem cell model of Shwachman-Diamond syndrome reveals apoptotic predisposition of hemoangiogenic progenitors.
Hamabata T, Umeda K, Kouzuki K, Tanaka T, Daifu T, Nodomi S, Saida S, Kato I, Baba S, Hiramatsu H, Osawa M, Niwa A, Saito MK, Kamikubo Y, Adachi S, Hashii Y, Shimada A, Watanabe H, Osafune K, Okita K, Nakahata T, Watanabe K, Takita J, Heike T. Hamabata T, et al. Among authors: tanaka t. Sci Rep. 2020 Sep 9;10(1):14859. doi: 10.1038/s41598-020-71844-8. Sci Rep. 2020. PMID: 32908229 Free PMC article.
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