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Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.
Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Greten TF, Duffy AG, Ciombor KK, Eyring AD, Lam BH, Joe A, Kang SP, Holdhoff M, Danilova L, Cope L, Meyer C, Zhou S, Goldberg RM, Armstrong DK, Bever KM, Fader AN, Taube J, Housseau F, Spetzler D, Xiao N, Pardoll DM, Papadopoulos N, Kinzler KW, Eshleman JR, Vogelstein B, Anders RA, Diaz LA Jr. Le DT, et al. Among authors: zhou s. Science. 2017 Jul 28;357(6349):409-413. doi: 10.1126/science.aan6733. Epub 2017 Jun 8. Science. 2017. PMID: 28596308 Free PMC article. Clinical Trial.
Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria.
Bettegowda C, Dang LH, Abrams R, Huso DL, Dillehay L, Cheong I, Agrawal N, Borzillary S, McCaffery JM, Watson EL, Lin KS, Bunz F, Baidoo K, Pomper MG, Kinzler KW, Vogelstein B, Zhou S. Bettegowda C, et al. Among authors: zhou s. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15083-8. doi: 10.1073/pnas.2036598100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657371 Free PMC article.
Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents.
Dang LH, Bettegowda C, Agrawal N, Cheong I, Huso D, Frost P, Loganzo F, Greenberger L, Barkoczy J, Pettit GR, Smith AB 3rd, Gurulingappa H, Khan S, Parmigiani G, Kinzler KW, Zhou S, Vogelstein B. Dang LH, et al. Among authors: zhou s. Cancer Biol Ther. 2004 Mar;3(3):326-37. doi: 10.4161/cbt.3.3.704. Epub 2004 Mar 12. Cancer Biol Ther. 2004. PMID: 14739784 Free article.
Bacteriolytic therapy can generate a potent immune response against experimental tumors.
Agrawal N, Bettegowda C, Cheong I, Geschwind JF, Drake CG, Hipkiss EL, Tatsumi M, Dang LH, Diaz LA Jr, Pomper M, Abusedera M, Wahl RL, Kinzler KW, Zhou S, Huso DL, Vogelstein B. Agrawal N, et al. Among authors: zhou s. Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15172-7. doi: 10.1073/pnas.0406242101. Epub 2004 Oct 7. Proc Natl Acad Sci U S A. 2004. PMID: 15471990 Free PMC article.
Pharmacologic and toxicologic evaluation of C. novyi-NT spores.
Diaz LA Jr, Cheong I, Foss CA, Zhang X, Peters BA, Agrawal N, Bettegowda C, Karim B, Liu G, Khan K, Huang X, Kohli M, Dang LH, Hwang P, Vogelstein A, Garrett-Mayer E, Kobrin B, Pomper M, Zhou S, Kinzler KW, Vogelstein B, Huso DL. Diaz LA Jr, et al. Among authors: zhou s. Toxicol Sci. 2005 Dec;88(2):562-75. doi: 10.1093/toxsci/kfi316. Epub 2005 Sep 14. Toxicol Sci. 2005. PMID: 16162850
The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT.
Bettegowda C, Huang X, Lin J, Cheong I, Kohli M, Szabo SA, Zhang X, Diaz LA Jr, Velculescu VE, Parmigiani G, Kinzler KW, Vogelstein B, Zhou S. Bettegowda C, et al. Among authors: zhou s. Nat Biotechnol. 2006 Dec;24(12):1573-80. doi: 10.1038/nbt1256. Epub 2006 Nov 19. Nat Biotechnol. 2006. PMID: 17115055 Free PMC article.
Spore coat architecture of Clostridium novyi NT spores.
Plomp M, McCaffery JM, Cheong I, Huang X, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B, Malkin AJ. Plomp M, et al. Among authors: zhou s. J Bacteriol. 2007 Sep;189(17):6457-68. doi: 10.1128/JB.00757-07. Epub 2007 Jun 22. J Bacteriol. 2007. PMID: 17586633 Free PMC article.
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