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Page 1
T Cell-Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection.
Moreira-Teixeira L, Redford PS, Stavropoulos E, Ghilardi N, Maynard CL, Weaver CT, Freitas do Rosário AP, Wu X, Langhorne J, O'Garra A. Moreira-Teixeira L, et al. Among authors: ghilardi n. J Immunol. 2017 Jul 15;199(2):613-623. doi: 10.4049/jimmunol.1601340. Epub 2017 Jun 5. J Immunol. 2017. PMID: 28584007 Free PMC article.
Type I IFN induces IL-10 production in an IL-27-independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in Mycobacterium tuberculosis-infected macrophages.
McNab FW, Ewbank J, Howes A, Moreira-Teixeira L, Martirosyan A, Ghilardi N, Saraiva M, O'Garra A. McNab FW, et al. Among authors: ghilardi n. J Immunol. 2014 Oct 1;193(7):3600-12. doi: 10.4049/jimmunol.1401088. Epub 2014 Sep 3. J Immunol. 2014. PMID: 25187652 Free PMC article.
A restricted role for TYK2 catalytic activity in human cytokine responses revealed by novel TYK2-selective inhibitors.
Sohn SJ, Barrett K, Van Abbema A, Chang C, Kohli PB, Kanda H, Smith J, Lai Y, Zhou A, Zhang B, Yang W, Williams K, Macleod C, Hurley CA, Kulagowski JJ, Lewin-Koh N, Dengler HS, Johnson AR, Ghilardi N, Zak M, Liang J, Blair WS, Magnuson S, Wu LC. Sohn SJ, et al. Among authors: ghilardi n. J Immunol. 2013 Sep 1;191(5):2205-16. doi: 10.4049/jimmunol.1202859. Epub 2013 Jul 26. J Immunol. 2013. PMID: 23894201 Free PMC article.
Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection.
Torrado E, Fountain JJ, Liao M, Tighe M, Reiley WW, Lai RP, Meintjes G, Pearl JE, Chen X, Zak DE, Thompson EG, Aderem A, Ghilardi N, Solache A, McKinstry KK, Strutt TM, Wilkinson RJ, Swain SL, Cooper AM. Torrado E, et al. Among authors: ghilardi n. J Exp Med. 2015 Aug 24;212(9):1449-63. doi: 10.1084/jem.20141520. Epub 2015 Aug 17. J Exp Med. 2015. PMID: 26282876 Free PMC article. Clinical Trial.
IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.
Vijayan D, Mohd Redzwan N, Avery DT, Wirasinha RC, Brink R, Walters G, Adelstein S, Kobayashi M, Gray P, Elliott M, Wong M, King C, Vinuesa CG, Ghilardi N, Ma CS, Tangye SG, Batten M. Vijayan D, et al. Among authors: ghilardi n. J Immunol. 2016 Oct 15;197(8):3008-3017. doi: 10.4049/jimmunol.1600652. Epub 2016 Sep 12. J Immunol. 2016. PMID: 27619997
IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available.
Khader SA, Pearl JE, Sakamoto K, Gilmartin L, Bell GK, Jelley-Gibbs DM, Ghilardi N, deSauvage F, Cooper AM. Khader SA, et al. Among authors: ghilardi n. J Immunol. 2005 Jul 15;175(2):788-95. doi: 10.4049/jimmunol.175.2.788. J Immunol. 2005. PMID: 16002675
71 results