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TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.
Kumar R, Mickael C, Kassa B, Gebreab L, Robinson JC, Koyanagi DE, Sanders L, Barthel L, Meadows C, Fox D, Irwin D, Li M, McKeon BA, Riddle S, Dale Brown R, Morgan LE, Evans CM, Hernandez-Saavedra D, Bandeira A, Maloney JP, Bull TM, Janssen WJ, Stenmark KR, Tuder RM, Graham BB. Kumar R, et al. Among authors: evans cm. Nat Commun. 2017 May 30;8:15494. doi: 10.1038/ncomms15494. Nat Commun. 2017. PMID: 28555642 Free PMC article.
Muc5b is required for airway defence.
Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM. Roy MG, et al. Among authors: evans se, evans cm. Nature. 2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8. Nature. 2014. PMID: 24317696 Free PMC article.
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF. Evans CM, et al. Nat Commun. 2015 Feb 17;6:6281. doi: 10.1038/ncomms7281. Nat Commun. 2015. PMID: 25687754 Free PMC article.
Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice.
Neudecker V, Brodsky KS, Clambey ET, Schmidt EP, Packard TA, Davenport B, Standiford TJ, Weng T, Fletcher AA, Barthel L, Masterson JC, Furuta GT, Cai C, Blackburn MR, Ginde AA, Graner MW, Janssen WJ, Zemans RL, Evans CM, Burnham EL, Homann D, Moss M, Kreth S, Zacharowski K, Henson PM, Eltzschig HK. Neudecker V, et al. Among authors: evans cm. Sci Transl Med. 2017 Sep 20;9(408):eaah5360. doi: 10.1126/scitranslmed.aah5360. Sci Transl Med. 2017. PMID: 28931657 Free PMC article.
Disulfide disruption reverses mucus dysfunction in allergic airway disease.
Morgan LE, Jaramillo AM, Shenoy SK, Raclawska D, Emezienna NA, Richardson VL, Hara N, Harder AQ, NeeDell JC, Hennessy CE, El-Batal HM, Magin CM, Grove Villalon DE, Duncan G, Hanes JS, Suk JS, Thornton DJ, Holguin F, Janssen WJ, Thelin WR, Evans CM. Morgan LE, et al. Among authors: evans cm. Nat Commun. 2021 Jan 11;12(1):249. doi: 10.1038/s41467-020-20499-0. Nat Commun. 2021. PMID: 33431872 Free PMC article.
240 results