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MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.
Saferding V, Puchner A, Goncalves-Alves E, Hofmann M, Bonelli M, Brunner JS, Sahin E, Niederreiter B, Hayer S, Kiener HP, Einwallner E, Nehmar R, Carapito R, Georgel P, Koenders MI, Boldin M, Schabbauer G, Kurowska-Stolarska M, Steiner G, Smolen JS, Redlich K, Blüml S. Saferding V, et al. Among authors: kiener hp. J Autoimmun. 2017 Aug;82:74-84. doi: 10.1016/j.jaut.2017.05.006. Epub 2017 May 22. J Autoimmun. 2017. PMID: 28545737 Free PMC article.
FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes.
Brandstetter B, Dalwigk K, Platzer A, Niederreiter B, Kartnig F, Fischer A, Vladimer GI, Byrne RA, Sevelda F, Holinka J, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T. Brandstetter B, et al. Among authors: kiener hp. Lab Invest. 2019 May;99(5):648-658. doi: 10.1038/s41374-018-0184-7. Epub 2019 Jan 24. Lab Invest. 2019. PMID: 30679758 Free article.
IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs.
Bonelli M, Dalwigk K, Platzer A, Olmos Calvo I, Hayer S, Niederreiter B, Holinka J, Sevelda F, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T. Bonelli M, et al. Among authors: kiener hp. Exp Mol Med. 2019 Jul 8;51(7):1-11. doi: 10.1038/s12276-019-0267-6. Exp Mol Med. 2019. PMID: 31285419 Free PMC article.
Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: regulation of expression and activation by interleukin-1 and tumor necrosis factor alpha.
Redlich K, Kiener HP, Schett G, Tohidast-Akrad M, Selzer E, Radda I, Stummvoll GH, Steiner CW, Gröger M, Bitzan P, Zenz P, Smolen JS, Steiner G. Redlich K, et al. Among authors: kiener hp. Arthritis Rheum. 2001 Feb;44(2):266-74. doi: 10.1002/1529-0131(200102)44:2<266::AID-ANR43>3.0.CO;2-G. Arthritis Rheum. 2001. PMID: 11229456 Free article.
mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation.
Karonitsch T, Kandasamy RK, Kartnig F, Herdy B, Dalwigk K, Niederreiter B, Holinka J, Sevelda F, Windhager R, Bilban M, Weichhart T, Säemann M, Pap T, Steiner G, Smolen JS, Kiener HP, Superti-Furga G. Karonitsch T, et al. Among authors: kiener hp. Cell Rep. 2018 May 15;23(7):2157-2167. doi: 10.1016/j.celrep.2018.04.044. Cell Rep. 2018. PMID: 29768212 Free PMC article.
Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs.
Schett G, Redlich K, Xu Q, Bizan P, Gröger M, Tohidast-Akrad M, Kiener H, Smolen J, Steiner G. Schett G, et al. J Clin Invest. 1998 Jul 15;102(2):302-11. doi: 10.1172/JCI2465. J Clin Invest. 1998. PMID: 9664071 Free PMC article.
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