Rizzo AA - Search Results

1

Identification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction.

Sail V, Rizzo AA, Chatterjee N, Dash RC, Ozen Z, Walker GC, Korzhnev DM, Hadden MK. Sail V, et al. Among authors: rizzo aa. ACS Chem Biol. 2017 Jul 21;12(7):1903-1912. doi: 10.1021/acschembio.6b01144. Epub 2017 Jun 9. ACS Chem Biol. 2017. PMID: 28541665 Free PMC article.

2

NMR structure of the human Rad18 zinc finger in complex with ubiquitin defines a class of UBZ domains in proteins linked to the DNA damage response.

Rizzo AA, Salerno PE, Bezsonova I, Korzhnev DM. Rizzo AA, et al. Biochemistry. 2014 Sep 23;53(37):5895-906. doi: 10.1021/bi500823h. Epub 2014 Sep 15. Biochemistry. 2014. PMID: 25162118

3

Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis.

Pustovalova Y, Magalhães MT, D'Souza S, Rizzo AA, Korza G, Walker GC, Korzhnev DM. Pustovalova Y, et al. Among authors: rizzo aa. Biochemistry. 2016 Apr 5;55(13):2043-53. doi: 10.1021/acs.biochem.5b01282. Epub 2016 Mar 24. Biochemistry. 2016. PMID: 26982350 Free PMC article.

4

NMR resonance assignments for the N-terminal domain of the δ subunit of the E. coli γ clamp loader complex.

Alyami EM, Rizzo AA, Beuning PJ, Korzhnev DM. Alyami EM, et al. Among authors: rizzo aa. Biomol NMR Assign. 2017 Oct;11(2):169-173. doi: 10.1007/s12104-017-9741-z. Epub 2017 Mar 6. Biomol NMR Assign. 2017. PMID: 28265855

5

Small molecule scaffolds that disrupt the Rev1-CT/RIR protein-protein interaction.

Ozen Z, Dash RC, McCarthy KR, Chow SA, Rizzo AA, Korzhnev DM, Hadden MK. Ozen Z, et al. Among authors: rizzo aa. Bioorg Med Chem. 2018 Aug 7;26(14):4301-4309. doi: 10.1016/j.bmc.2018.07.029. Epub 2018 Jul 19. Bioorg Med Chem. 2018. PMID: 30037752

6

Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex.

Rizzo AA, Vassel FM, Chatterjee N, D'Souza S, Li Y, Hao B, Hemann MT, Walker GC, Korzhnev DM. Rizzo AA, et al. Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8191-E8200. doi: 10.1073/pnas.1801149115. Epub 2018 Aug 15. Proc Natl Acad Sci U S A. 2018. PMID: 30111544 Free PMC article.

7

Structural Approach To Identify a Lead Scaffold That Targets the Translesion Synthesis Polymerase Rev1.

Dash RC, Ozen Z, Rizzo AA, Lim S, Korzhnev DM, Hadden MK. Dash RC, et al. Among authors: rizzo aa. J Chem Inf Model. 2018 Nov 26;58(11):2266-2277. doi: 10.1021/acs.jcim.8b00535. Epub 2018 Oct 19. J Chem Inf Model. 2018. PMID: 30289707

8

Dynamics of the E. coli β-Clamp Dimer Interface and Its Influence on DNA Loading.

Koleva BN, Gokcan H, Rizzo AA, Lim S, Jeanne Dit Fouque K, Choy A, Liriano ML, Fernandez-Lima F, Korzhnev DM, Cisneros GA, Beuning PJ. Koleva BN, et al. Among authors: rizzo aa. Biophys J. 2019 Aug 6;117(3):587-601. doi: 10.1016/j.bpj.2019.06.035. Epub 2019 Jul 5. Biophys J. 2019. PMID: 31349986 Free PMC article.

9

Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev1-CT/RIR Protein-Protein Interaction.

Dash RC, Ozen Z, McCarthy KR, Chatterjee N, Harris CA, Rizzo AA, Walker GC, Korzhnev DM, Hadden MK. Dash RC, et al. Among authors: rizzo aa. ChemMedChem. 2019 Sep 4;14(17):1610-1617. doi: 10.1002/cmdc.201900307. Epub 2019 Aug 21. ChemMedChem. 2019. PMID: 31361935 Free PMC article.

10

The Rev1-Polζ translesion synthesis mutasome: Structure, interactions and inhibition.

Rizzo AA, Korzhnev DM. Rizzo AA, et al. Enzymes. 2019;45:139-181. doi: 10.1016/bs.enz.2019.07.001. Epub 2019 Aug 9. Enzymes. 2019. PMID: 31627876 Free PMC article. Review.

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