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Page 1
Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases.
Petrassi M, Barber R, Be C, Beach S, Cox B, D'Souza AM, Duggan N, Hussey M, Fox R, Hunt P, Jarai G, Kosaka T, Oakley P, Patel V, Press N, Rowlands D, Scheufler C, Schmidt O, Srinivas H, Turner M, Turner R, Westwick J, Wolfreys A, Pathan N, Watson S, Thomas M. Petrassi M, et al. Among authors: oakley p. Front Pharmacol. 2017 May 5;8:240. doi: 10.3389/fphar.2017.00240. eCollection 2017. Front Pharmacol. 2017. PMID: 28529483 Free PMC article.
4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitors.
Churcher I, Beher D, Best JD, Castro JL, Clarke EE, Gentry A, Harrison T, Hitzel L, Kay E, Kerrad S, Lewis HD, Morentin-Gutierrez P, Mortishire-Smith R, Oakley PJ, Reilly M, Shaw DE, Shearman MS, Teall MR, Williams S, Wrigley JD. Churcher I, et al. Among authors: oakley pj. Bioorg Med Chem Lett. 2006 Jan 15;16(2):280-4. doi: 10.1016/j.bmcl.2005.10.009. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275079
Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.
Cole AG, Metzger A, Brescia MR, Qin LY, Appell KC, Brain CT, Hallett A, Ganju P, Denholm AA, Wareing JR, Ritchie TJ, Drake GM, Bevan SJ, MacGloinn A, McBryde A, Patel V, Oakley PJ, Nunez X, Gstach H, Schneider P, Baldwin JJ, Dolle RE, McDonald E, Henderson I. Cole AG, et al. Among authors: oakley pj. Bioorg Med Chem Lett. 2009 Jan 1;19(1):119-22. doi: 10.1016/j.bmcl.2008.11.005. Epub 2008 Nov 6. Bioorg Med Chem Lett. 2009. PMID: 19014884
Aryl sulfones: a new class of gamma-secretase inhibitors.
Teall M, Oakley P, Harrison T, Shaw D, Kay E, Elliott J, Gerhard U, Castro JL, Shearman M, Ball RG, Tsou NN. Teall M, et al. Among authors: oakley p. Bioorg Med Chem Lett. 2005 May 16;15(10):2685-8. doi: 10.1016/j.bmcl.2004.12.017. Bioorg Med Chem Lett. 2005. PMID: 15863342
Prediction of retention for sulfonamides in supercritical fluid chromatography.
Cazenave-Gassiot A, Boughtflower R, Caldwell J, Coxhead R, Hitzel L, Lane S, Oakley P, Holyoak C, Pullen F, Langley GJ. Cazenave-Gassiot A, et al. Among authors: oakley p. J Chromatogr A. 2008 May 2;1189(1-2):254-65. doi: 10.1016/j.chroma.2007.10.020. Epub 2007 Oct 12. J Chromatogr A. 2008. PMID: 17977551
Differences in Sensorimotor Integration, Cervical Sensorimotor Control, and Cognitive-Motor Dual Tasking Costs in Chronic Non-Specific Neck Pain Patients with High vs. Low Catastrophizing Tendencies Compared to Healthy Controls.
Moustafa IM, Ahbouch A, Zadeh SAM, Shousha T, Oakley PA, Harrison D. Moustafa IM, et al. Among authors: oakley pa. Behav Brain Res. 2025 Jan 15:115434. doi: 10.1016/j.bbr.2025.115434. Online ahead of print. Behav Brain Res. 2025. PMID: 39824225 Free article.
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