Imaeda T - Search Results

1

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2'-piperidin)-1-ones as potassium-competitive acid blockers.

Imaeda T, Ono K, Nakai K, Hori Y, Matsukawa J, Takagi T, Fujioka Y, Tarui N, Kondo M, Imanishi A, Inatomi N, Kajino M, Itoh F, Nishida H. Imaeda T, et al. Bioorg Med Chem. 2017 Jul 15;25(14):3719-3735. doi: 10.1016/j.bmc.2017.05.012. Epub 2017 May 6. Bioorg Med Chem. 2017. PMID: 28522264

2

A new class of potent nonpeptide luteinizing hormone-releasing hormone (LHRH) antagonists: design and synthesis of 2-phenylimidazo[1,2-a]pyrimidin-5-ones.

Sasaki S, Imaeda T, Hayase Y, Shimizu Y, Kasai S, Cho N, Harada M, Suzuki N, Furuya S, Fujino M. Sasaki S, et al. Among authors: imaeda t. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2073-7. doi: 10.1016/s0960-894x(02)00372-4. Bioorg Med Chem Lett. 2002. PMID: 12127507

3

Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists.

Imada T, Cho N, Imaeda T, Hayase Y, Sasaki S, Kasai S, Harada M, Matsumoto H, Endo S, Suzuki N, Furuya S. Imada T, et al. Among authors: imaeda t. J Med Chem. 2006 Jun 29;49(13):3809-25. doi: 10.1021/jm0512894. J Med Chem. 2006. PMID: 16789738

4

BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression.

Kimura H, Sato Y, Tajima Y, Suzuki H, Yukitake H, Imaeda T, Kajino M, Oki H, Takizawa M, Tanida S. Kimura H, et al. Among authors: imaeda t. Chem Biol. 2010 Dec 22;17(12):1282-94. doi: 10.1016/j.chembiol.2010.10.011. Chem Biol. 2010. PMID: 21168764

5

BTZO-15, an ARE-activator, ameliorates DSS- and TNBS-induced colitis in rats.

Yukitake H, Kimura H, Suzuki H, Tajima Y, Sato Y, Imaeda T, Kajino M, Takizawa M. Yukitake H, et al. Among authors: imaeda t. PLoS One. 2011;6(8):e23256. doi: 10.1371/journal.pone.0023256. Epub 2011 Aug 10. PLoS One. 2011. PMID: 21853095 Free PMC article.

6

Discovery, synthesis, and structure-activity relationship of 6-aminomethyl-7,8-dihydronaphthalenes as human melanin-concentrating hormone receptor 1 antagonists.

Kamata M, Yamashita T, Imaeda T, Tanaka T, Terauchi J, Miyamoto M, Ora T, Tawada M, Endo S, Takekawa S, Asami A, Suzuki N, Nagisa Y, Nakano Y, Watanabe K, Ogino H, Kato K, Kato K, Ishihara Y. Kamata M, et al. Among authors: imaeda t. Bioorg Med Chem. 2011 Sep 15;19(18):5539-52. doi: 10.1016/j.bmc.2011.07.038. Epub 2011 Jul 26. Bioorg Med Chem. 2011. PMID: 21856163

7

Melanin-concentrating hormone receptor 1 antagonists. Synthesis and structure-activity relationships of novel 3-(aminomethyl)quinolines.

Kamata M, Yamashita T, Imaeda T, Tanaka T, Masada S, Kamaura M, Kasai S, Hara R, Sasaki S, Takekawa S, Asami A, Kaisho T, Suzuki N, Ashina S, Ogino H, Nakano Y, Nagisa Y, Kato K, Kato K, Ishihara Y. Kamata M, et al. Among authors: imaeda t. J Med Chem. 2012 Mar 8;55(5):2353-66. doi: 10.1021/jm201596h. Epub 2012 Feb 22. J Med Chem. 2012. PMID: 22309223

8

Design, synthesis, and biological evaluation of a series of piperazine ureas as fatty acid amide hydrolase inhibitors.

Kono M, Matsumoto T, Imaeda T, Kawamura T, Fujimoto S, Kosugi Y, Odani T, Shimizu Y, Matsui H, Shimojo M, Kori M. Kono M, et al. Among authors: imaeda t. Bioorg Med Chem. 2014 Feb 15;22(4):1468-78. doi: 10.1016/j.bmc.2013.12.023. Epub 2013 Dec 20. Bioorg Med Chem. 2014. PMID: 24440478

9

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action.

Nishida H, Arikawa Y, Hirase K, Imaeda T, Inatomi N, Hori Y, Matsukawa J, Fujioka Y, Hamada T, Iida M, Nishitani M, Imanishi A, Fukui H, Itoh F, Kajino M. Nishida H, et al. Among authors: imaeda t. Bioorg Med Chem. 2017 Jul 1;25(13):3298-3314. doi: 10.1016/j.bmc.2017.04.014. Epub 2017 Apr 13. Bioorg Med Chem. 2017. PMID: 28442261

10

Design and synthesis of 6-methylpyridin-2-one derivatives as novel and potent GluN2A positive allosteric modulators for the treatment of cognitive impairment.

Yukawa T, Yamashita T, Imaeda T, Kakei H, Hashizume S, Nakamura M, Daini M, Okabe A, Nakashima K, Harada A, Narita N, Bettini E, Ugolini A, Corsi M, Hasui T. Yukawa T, et al. Among authors: imaeda t. Bioorg Med Chem. 2023 Feb 1;79:117150. doi: 10.1016/j.bmc.2022.117150. Epub 2022 Dec 24. Bioorg Med Chem. 2023. PMID: 36640594 Free article.

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