Chaput E - Search Results

1

Dalcetrapib and anacetrapib differently impact HDL structure and function in rabbits and monkeys.

Brodeur MR, Rhainds D, Charpentier D, Mihalache-Avram T, Mecteau M, Brand G, Chaput E, Perez A, Niesor EJ, Rhéaume E, Maugeais C, Tardif JC. Brodeur MR, et al. Among authors: chaput e. J Lipid Res. 2017 Jul;58(7):1282-1291. doi: 10.1194/jlr.M068940. Epub 2017 May 17. J Lipid Res. 2017. PMID: 28515138 Free PMC article.

2

Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport.

Niesor EJ, Magg C, Ogawa N, Okamoto H, von der Mark E, Matile H, Schmid G, Clerc RG, Chaput E, Blum-Kaelin D, Huber W, Thoma R, Pflieger P, Kakutani M, Takahashi D, Dernick G, Maugeais C. Niesor EJ, et al. Among authors: chaput e. J Lipid Res. 2010 Dec;51(12):3443-54. doi: 10.1194/jlr.M008706. Epub 2010 Sep 22. J Lipid Res. 2010. PMID: 20861162 Free PMC article.

3

Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects.

Niesor EJ, Chaput E, Staempfli A, Blum D, Derks M, Kallend D. Niesor EJ, et al. Among authors: chaput e. Atherosclerosis. 2011 Dec;219(2):761-7. doi: 10.1016/j.atherosclerosis.2011.09.017. Epub 2011 Sep 16. Atherosclerosis. 2011. PMID: 21982411 Clinical Trial.

4

Effect of compounds affecting ABCA1 expression and CETP activity on the HDL pathway involved in intestinal absorption of lutein and zeaxanthin.

Niesor EJ, Chaput E, Mary JL, Staempfli A, Topp A, Stauffer A, Wang H, Durrwell A. Niesor EJ, et al. Among authors: chaput e. Lipids. 2014 Dec;49(12):1233-43. doi: 10.1007/s11745-014-3958-8. Epub 2014 Oct 10. Lipids. 2014. PMID: 25300953

5

Studies in mice, hamsters, and rats demonstrate that repression of hepatic apoA-I expression by taurocholic acid in mice is not mediated by the farnesoid-X-receptor.

Gardès C, Blum D, Bleicher K, Chaput E, Ebeling M, Hartman P, Handschin C, Richter H, Benson GM. Gardès C, et al. Among authors: chaput e. J Lipid Res. 2011 Jun;52(6):1188-1199. doi: 10.1194/jlr.M012542. Epub 2011 Apr 4. J Lipid Res. 2011. PMID: 21464203 Free PMC article.

6

Differential regulation of bile acid and cholesterol metabolism by the farnesoid X receptor in Ldlr -/- mice versus hamsters.

Gardès C, Chaput E, Staempfli A, Blum D, Richter H, Benson GM. Gardès C, et al. Among authors: chaput e. J Lipid Res. 2013 May;54(5):1283-99. doi: 10.1194/jlr.M033423. Epub 2013 Feb 21. J Lipid Res. 2013. PMID: 23431047 Free PMC article.

7

Characterization of post-surgical alterations in the bile duct-cannulated rat.

Bachir-Cherif D, Blum D, Braendli-Baiocco A, Chaput E, Pacheco GC, Flint N, Haiker M, Hoflack JC, Justies N, Neff R, Starke V, Steiner G, Tournillac CA, Singer T, Ubeaud-Séquier G, Schuler F. Bachir-Cherif D, et al. Among authors: chaput e. Xenobiotica. 2011 Aug;41(8):701-11. doi: 10.3109/00498254.2011.565819. Epub 2011 Apr 27. Xenobiotica. 2011. PMID: 21521079

8

Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties.

Richter HG, Benson GM, Bleicher KH, Blum D, Chaput E, Clemann N, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S. Richter HG, et al. Among authors: chaput e. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1134-40. doi: 10.1016/j.bmcl.2010.12.123. Epub 2010 Dec 31. Bioorg Med Chem Lett. 2011. PMID: 21269824

9

Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes.

Richter HG, Benson GM, Blum D, Chaput E, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S, Bleicher KH. Richter HG, et al. Among authors: chaput e. Bioorg Med Chem Lett. 2011 Jan 1;21(1):191-4. doi: 10.1016/j.bmcl.2010.11.039. Epub 2010 Nov 12. Bioorg Med Chem Lett. 2011. PMID: 21134747

10

6-Alkoxy-5-aryl-3-pyridinecarboxamides, a new series of bioavailable cannabinoid receptor type 1 (CB1) antagonists including peripherally selective compounds.

Röver S, Andjelkovic M, Bénardeau A, Chaput E, Guba W, Hebeisen P, Mohr S, Nettekoven M, Obst U, Richter WF, Ullmer C, Waldmeier P, Wright MB. Röver S, et al. Among authors: chaput e. J Med Chem. 2013 Dec 27;56(24):9874-96. doi: 10.1021/jm4010708. Epub 2013 Nov 20. J Med Chem. 2013. PMID: 24175572

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