Dekan Z - Search Results

1

Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities.

Dekan Z, Headey SJ, Scanlon M, Baldo BA, Lee TH, Aguilar MI, Deuis JR, Vetter I, Elliott AG, Amado M, Cooper MA, Alewood D, Alewood PF. Dekan Z, et al. Angew Chem Int Ed Engl. 2017 Jul 10;56(29):8495-8499. doi: 10.1002/anie.201703360. Epub 2017 Jun 13. Angew Chem Int Ed Engl. 2017. PMID: 28513074

2

Total synthesis of human hepcidin through regioselective disulfide-bond formation by using the safety-catch cysteine protecting group 4,4'-dimethylsulfinylbenzhydryl.

Dekan Z, Mobli M, Pennington MW, Fung E, Nemeth E, Alewood PF. Dekan Z, et al. Angew Chem Int Ed Engl. 2014 Mar 10;53(11):2931-4. doi: 10.1002/anie.201310103. Epub 2014 Feb 7. Angew Chem Int Ed Engl. 2014. PMID: 24604812

3

Identification and Characterization of ProTx-III [μ-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.

Cardoso FC, Dekan Z, Rosengren KJ, Erickson A, Vetter I, Deuis JR, Herzig V, Alewood PF, King GF, Lewis RJ. Cardoso FC, et al. Among authors: dekan z. Mol Pharmacol. 2015 Aug;88(2):291-303. doi: 10.1124/mol.115.098178. Epub 2015 May 15. Mol Pharmacol. 2015. PMID: 25979003

4

Development of a μO-Conotoxin Analogue with Improved Lipid Membrane Interactions and Potency for the Analgesic Sodium Channel NaV1.8.

Deuis JR, Dekan Z, Inserra MC, Lee TH, Aguilar MI, Craik DJ, Lewis RJ, Alewood PF, Mobli M, Schroeder CI, Henriques ST, Vetter I. Deuis JR, et al. Among authors: dekan z. J Biol Chem. 2016 May 27;291(22):11829-42. doi: 10.1074/jbc.M116.721662. Epub 2016 Mar 29. J Biol Chem. 2016. PMID: 27026701 Free PMC article.

5

Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity.

Jin AH, Dekan Z, Smout MJ, Wilson D, Dutertre S, Vetter I, Lewis RJ, Loukas A, Daly NL, Alewood PF. Jin AH, et al. Among authors: dekan z. Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14973-14976. doi: 10.1002/anie.201708927. Epub 2017 Oct 24. Angew Chem Int Ed Engl. 2017. PMID: 28984021

6

Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus.

Cardoso FC, Dekan Z, Smith JJ, Deuis JR, Vetter I, Herzig V, Alewood PF, King GF, Lewis RJ. Cardoso FC, et al. Among authors: dekan z. Br J Pharmacol. 2017 Aug;174(15):2528-2544. doi: 10.1111/bph.13865. Epub 2017 Jun 27. Br J Pharmacol. 2017. PMID: 28542706 Free PMC article.

7

Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen.

Mueller A, Starobova H, Morgan M, Dekan Z, Cheneval O, Schroeder CI, Alewood PF, Deuis JR, Vetter I. Mueller A, et al. Among authors: dekan z. Pain. 2019 Aug;160(8):1766-1780. doi: 10.1097/j.pain.0000000000001567. Pain. 2019. PMID: 31335646

8

Addition of K22 Converts Spider Venom Peptide Pme2a from an Activator to an Inhibitor of Na_V1.7.

Yin K, Deuis JR, Dekan Z, Jin AH, Alewood PF, King GF, Herzig V, Vetter I. Yin K, et al. Among authors: dekan z. Biomedicines. 2020 Feb 19;8(2):37. doi: 10.3390/biomedicines8020037. Biomedicines. 2020. PMID: 32092883 Free PMC article.

9

It Takes Two: Dimerization Is Essential for the Broad-Spectrum Predatory and Defensive Activities of the Venom Peptide Mp1a from the Jack Jumper Ant Myrmecia pilosula.

Nixon SA, Dekan Z, Robinson SD, Guo S, Vetter I, Kotze AC, Alewood PF, King GF, Herzig V. Nixon SA, et al. Among authors: dekan z. Biomedicines. 2020 Jun 30;8(7):185. doi: 10.3390/biomedicines8070185. Biomedicines. 2020. PMID: 32629771 Free PMC article.

10

α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure.

Dekan Z, Vetter I, Daly NL, Craik DJ, Lewis RJ, Alewood PF. Dekan Z, et al. J Am Chem Soc. 2011 Oct 12;133(40):15866-9. doi: 10.1021/ja206408q. Epub 2011 Sep 15. J Am Chem Soc. 2011. PMID: 21899353

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