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Page 1
Pentastatin, a matrikine of the collagen IVα5, is a novel endogenous mediator of pulmonary endothelial dysfunction.
Mutgan AC, Jandl K, Radic N, Valzano F, Kolb D, Hoffmann J, Foris V, Wilhelm J, Boehm PM, Hoetzenecker K, Olschewski A, Olschewski H, Heinemann A, Wygrecka M, Marsh LM, Kwapiszewska G. Mutgan AC, et al. Among authors: wygrecka m. Am J Physiol Cell Physiol. 2023 Nov 1;325(5):C1294-C1312. doi: 10.1152/ajpcell.00391.2023. Epub 2023 Sep 11. Am J Physiol Cell Physiol. 2023. PMID: 37694286 Free PMC article.
Alveolar oxidative stress is associated with elevated levels of nonenzymatic low-molecular-weight antioxidants in patients with different forms of chronic fibrosing interstitial lung diseases.
Markart P, Luboeinski T, Korfei M, Schmidt R, Wygrecka M, Mahavadi P, Mayer K, Wilhelm J, Seeger W, Guenther A, Ruppert C. Markart P, et al. Among authors: wygrecka m. Antioxid Redox Signal. 2009 Feb;11(2):227-40. doi: 10.1089/ars.2008.2105. Antioxid Redox Signal. 2009. PMID: 18783310
Comparative proteomic analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF) and lung transplant donor lungs.
Korfei M, Schmitt S, Ruppert C, Henneke I, Markart P, Loeh B, Mahavadi P, Wygrecka M, Klepetko W, Fink L, Bonniaud P, Preissner KT, Lochnit G, Schaefer L, Seeger W, Guenther A. Korfei M, et al. Among authors: wygrecka m. J Proteome Res. 2011 May 6;10(5):2185-205. doi: 10.1021/pr1009355. Epub 2011 Mar 29. J Proteome Res. 2011. PMID: 21319792
Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury.
Wygrecka M, Kosanovic D, Wujak L, Reppe K, Henneke I, Frey H, Didiasova M, Kwapiszewska G, Marsh LM, Baal N, Hackstein H, Zakrzewicz D, Müller-Redetzky HC, de Maat S, Maas C, Nolte MW, Panousis C, Schermuly RT, Seeger W, Witzenrath M, Schaefer L, Markart P. Wygrecka M, et al. Am J Respir Crit Care Med. 2017 Jul 15;196(2):186-199. doi: 10.1164/rccm.201604-0712OC. Am J Respir Crit Care Med. 2017. PMID: 28005404
Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors.
Didiasova M, Singh R, Wilhelm J, Kwapiszewska G, Wujak L, Zakrzewicz D, Schaefer L, Markart P, Seeger W, Lauth M, Wygrecka M. Didiasova M, et al. Among authors: wygrecka m. FASEB J. 2017 May;31(5):1916-1928. doi: 10.1096/fj.201600892RR. Epub 2017 Feb 1. FASEB J. 2017. PMID: 28148565
Because GLI transcription factors are not only crucial for Hh-mediated changes but are also required as mediators of TGF-beta signaling, our findings suggest that pirfenidone exerts its clinically beneficial effects through dual Hh/TGF-beta inhibition by targeting the GLI2 protei …
Because GLI transcription factors are not only crucial for Hh-mediated changes but are also required as mediators of TGF-beta signaling, our …
FXII promotes proteolytic processing of the LRP1 ectodomain.
Wujak L, Hesse C, Sewald K, Jonigk D, Braubach P, Warnecke G, Fieguth HG, Braun A, Lochnit G, Markart P, Schaefer L, Wygrecka M. Wujak L, et al. Among authors: wygrecka m. Biochim Biophys Acta Gen Subj. 2017 Aug;1861(8):2088-2098. doi: 10.1016/j.bbagen.2017.05.023. Epub 2017 May 25. Biochim Biophys Acta Gen Subj. 2017. PMID: 28552561
128 results