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9,486 results

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Page 1
A novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathways.
Shima H, Sasaki K, Suzuki T, Mukawa C, Obara T, Oba Y, Matsuo A, Kobayashi T, Mishima E, Watanabe S, Akiyama Y, Kikuchi K, Matsuhashi T, Oikawa Y, Nanto F, Akiyama Y, Ho HJ, Suzuki C, Saigusa D, Masamune A, Tomioka Y, Masaki T, Ito S, Hayashi KI, Abe T. Shima H, et al. Among authors: ito s. Sci Rep. 2017 May 15;7(1):1884. doi: 10.1038/s41598-017-01702-7. Sci Rep. 2017. PMID: 28507324 Free PMC article.
Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases.
Suzuki T, Yamaguchi H, Kikusato M, Matsuhashi T, Matsuo A, Sato T, Oba Y, Watanabe S, Minaki D, Saigusa D, Shimbo H, Mori N, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Yuri A, Kikuchi K, Toyohara T, Suzuki C, Kohzuki M, Anzai J, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Ito S, Osaka H, Hayashi K, Abe T. Suzuki T, et al. Among authors: ito s. Tohoku J Exp Med. 2015 Jul;236(3):225-32. doi: 10.1620/tjem.236.225. Tohoku J Exp Med. 2015. PMID: 26118651 Free article.
Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA3.
Akiyama Y, Kikuchi K, Saigusa D, Suzuki T, Takeuchi Y, Mishima E, Yamamoto Y, Ishida A, Sugawara D, Jinno D, Shima H, Toyohara T, Suzuki C, Souma T, Moriguchi T, Tomioka Y, Ito S, Abe T. Akiyama Y, et al. Among authors: ito s. PLoS One. 2013 Jul 9;8(7):e66518. doi: 10.1371/journal.pone.0066518. Print 2013. PLoS One. 2013. PMID: 23874392 Free PMC article.
Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage.
Suzuki T, Yamaguchi H, Kikusato M, Hashizume O, Nagatoishi S, Matsuo A, Sato T, Kudo T, Matsuhashi T, Murayama K, Ohba Y, Watanabe S, Kanno S, Minaki D, Saigusa D, Shinbo H, Mori N, Yuri A, Yokoro M, Mishima E, Shima H, Akiyama Y, Takeuchi Y, Kikuchi K, Toyohara T, Suzuki C, Ichimura T, Anzai J, Kohzuki M, Mano N, Kure S, Yanagisawa T, Tomioka Y, Toyomizu M, Tsumoto K, Nakada K, Bonventre JV, Ito S, Osaka H, Hayashi K, Abe T. Suzuki T, et al. Among authors: ito s. J Am Soc Nephrol. 2016 Jul;27(7):1925-32. doi: 10.1681/ASN.2015060623. Epub 2015 Nov 25. J Am Soc Nephrol. 2016. PMID: 26609120 Free PMC article.
Metabolic alterations by indoxyl sulfate in skeletal muscle induce uremic sarcopenia in chronic kidney disease.
Sato E, Mori T, Mishima E, Suzuki A, Sugawara S, Kurasawa N, Saigusa D, Miura D, Morikawa-Ichinose T, Saito R, Oba-Yabana I, Oe Y, Kisu K, Naganuma E, Koizumi K, Mokudai T, Niwano Y, Kudo T, Suzuki C, Takahashi N, Sato H, Abe T, Niwa T, Ito S. Sato E, et al. Among authors: ito s. Sci Rep. 2016 Nov 10;6:36618. doi: 10.1038/srep36618. Sci Rep. 2016. PMID: 27830716 Free PMC article.
Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS-based metabolomics approach.
Mishima E, Fukuda S, Mukawa C, Yuri A, Kanemitsu Y, Matsumoto Y, Akiyama Y, Fukuda NN, Tsukamoto H, Asaji K, Shima H, Kikuchi K, Suzuki C, Suzuki T, Tomioka Y, Soga T, Ito S, Abe T. Mishima E, et al. Among authors: ito s. Kidney Int. 2017 Sep;92(3):634-645. doi: 10.1016/j.kint.2017.02.011. Epub 2017 Apr 8. Kidney Int. 2017. PMID: 28396122 Free article.
Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases.
Matsuhashi T, Sato T, Kanno SI, Suzuki T, Matsuo A, Oba Y, Kikusato M, Ogasawara E, Kudo T, Suzuki K, Ohara O, Shimbo H, Nanto F, Yamaguchi H, Saigusa D, Mukaiyama Y, Watabe A, Kikuchi K, Shima H, Mishima E, Akiyama Y, Oikawa Y, Hsin-Jung HO, Akiyama Y, Suzuki C, Uematsu M, Ogata M, Kumagai N, Toyomizu M, Hozawa A, Mano N, Owada Y, Aiba S, Yanagisawa T, Tomioka Y, Kure S, Ito S, Nakada K, Hayashi KI, Osaka H, Abe T. Matsuhashi T, et al. Among authors: ito s. EBioMedicine. 2017 Jun;20:27-38. doi: 10.1016/j.ebiom.2017.05.016. Epub 2017 May 13. EBioMedicine. 2017. PMID: 28579242 Free PMC article.
Canagliflozin reduces plasma uremic toxins and alters the intestinal microbiota composition in a chronic kidney disease mouse model.
Mishima E, Fukuda S, Kanemitsu Y, Saigusa D, Mukawa C, Asaji K, Matsumoto Y, Tsukamoto H, Tachikawa T, Tsukimi T, Fukuda NN, Ho HJ, Kikuchi K, Suzuki C, Nanto F, Suzuki T, Ito S, Soga T, Tomioka Y, Abe T. Mishima E, et al. Among authors: ito s. Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F824-F833. doi: 10.1152/ajprenal.00314.2017. Epub 2017 Nov 22. Am J Physiol Renal Physiol. 2018. PMID: 29167170 Free article.
The guanylate cyclase C agonist linaclotide ameliorates the gut-cardio-renal axis in an adenine-induced mouse model of chronic kidney disease.
Nanto-Hara F, Kanemitsu Y, Fukuda S, Kikuchi K, Asaji K, Saigusa D, Iwasaki T, Ho HJ, Mishima E, Suzuki T, Suzuki C, Tsukimi T, Matsuhashi T, Oikawa Y, Akiyama Y, Kure S, Owada Y, Tomioka Y, Soga T, Ito S, Abe T. Nanto-Hara F, et al. Among authors: ito s. Nephrol Dial Transplant. 2020 Feb 1;35(2):250-264. doi: 10.1093/ndt/gfz126. Nephrol Dial Transplant. 2020. PMID: 31411705
9,486 results