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The mitochondrial respiratory chain is essential for haematopoietic stem cell function.
Ansó E, Weinberg SE, Diebold LP, Thompson BJ, Malinge S, Schumacker PT, Liu X, Zhang Y, Shao Z, Steadman M, Marsh KM, Xu J, Crispino JD, Chandel NS. Ansó E, et al. Among authors: chandel ns. Nat Cell Biol. 2017 Jun;19(6):614-625. doi: 10.1038/ncb3529. Epub 2017 May 15. Nat Cell Biol. 2017. PMID: 28504706 Free PMC article.
Inhibition of cytochrome-c oxidase activity during prolonged hypoxia.
Chandel N, Budinger GR, Kemp RA, Schumacker PT. Chandel N, et al. Am J Physiol. 1995 Jun;268(6 Pt 1):L918-25. doi: 10.1152/ajplung.1995.268.6.L918. Am J Physiol. 1995. PMID: 7611433
However, rat hepatocytes demonstrate a reversible suppression of respiration and an increase in NAD(P)H concentration during prolonged (2-24 h), but not acute hypoxia [P. T. Schumacker, N. Chandel, and A. G. N. Augusti. Am. J. Physiol. 265 (Lung Cell. Mol. Physiol. 9): L39 …
However, rat hepatocytes demonstrate a reversible suppression of respiration and an increase in NAD(P)H concentration during prolonged (2-24 …
324 results