Zhang L - Search Results

1

Paracrine release of IL-2 and anti-CTLA-4 enhances the ability of artificial polymer antigen-presenting cells to expand antigen-specific T cells and inhibit tumor growth in a mouse model.

Zhang L, Wang L, Shahzad KA, Xu T, Wan X, Pei W, Shen C. Zhang L, et al. Cancer Immunol Immunother. 2017 Sep;66(9):1229-1241. doi: 10.1007/s00262-017-2016-9. Epub 2017 May 13. Cancer Immunol Immunother. 2017. PMID: 28501941 Free PMC article.

2

A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide-Autoreactive CD4⁺ and CD8⁺ T Cells.

Wan X, Pei W, Shahzad KA, Zhang L, Song S, Jin X, Wang L, Zhao C, Shen C. Wan X, et al. Among authors: zhang l. J Immunol. 2018 Aug 15;201(4):1194-1210. doi: 10.4049/jimmunol.1800108. Epub 2018 Jul 9. J Immunol. 2018. PMID: 29987163

3

An Artificial Antigen-Presenting Cell Delivering 11 Immune Molecules Expands Tumor Antigen-Specific CTLs in Ex Vivo and In Vivo Murine Melanoma Models.

Zhang L, Song S, Jin X, Wan X, Shahzad KA, Pei W, Zhao C, Shen C. Zhang L, et al. Cancer Immunol Res. 2019 Jul;7(7):1188-1201. doi: 10.1158/2326-6066.CIR-18-0881. Epub 2019 May 21. Cancer Immunol Res. 2019. PMID: 31113806

4

Frequency and reactivity of antigen-specific T cells were concurrently measured through the combination of artificial antigen-presenting cell, MACS and ELISPOT.

Shen C, Xu T, Wu Y, Li X, Xia L, Wang W, Shahzad KA, Zhang L, Wan X, Qiu J. Shen C, et al. Among authors: zhang l. Sci Rep. 2017 Nov 27;7(1):16400. doi: 10.1038/s41598-017-16549-1. Sci Rep. 2017. PMID: 29180767 Free PMC article.

5

An Antigen-Presenting and Apoptosis-Inducing Polymer Microparticle Prolongs Alloskin Graft Survival by Selectively and Markedly Depleting Alloreactive CD8⁺ T Cells.

Wang W, Shahzad KA, Li M, Zhang A, Zhang L, Xu T, Wan X, Shen C. Wang W, et al. Among authors: zhang l, zhang a. Front Immunol. 2017 Jun 9;8:657. doi: 10.3389/fimmu.2017.00657. eCollection 2017. Front Immunol. 2017. PMID: 28649247 Free PMC article.

6

PEGylated and CD47-conjugated nanoellipsoidal artificial antigen-presenting cells minimize phagocytosis and augment anti-tumor T-cell responses.

Song S, Jin X, Zhang L, Zhao C, Ding Y, Ang Q, Khaidav O, Shen C. Song S, et al. Among authors: zhang l. Int J Nanomedicine. 2019 Apr 8;14:2465-2483. doi: 10.2147/IJN.S195828. eCollection 2019. Int J Nanomedicine. 2019. PMID: 31040669 Free PMC article.

7

Design and Optimization of PLGA Particles to Deliver Immunomodulatory Drugs for the Prevention of Skin Allograft Rejection.

Shahzad KA, Naeem M, Zhang L, Wan X, Song S, Pei W, Zhao C, Jin X, Shen C. Shahzad KA, et al. Among authors: zhang l. Immunol Invest. 2020 Oct;49(7):840-857. doi: 10.1080/08820139.2019.1695134. Epub 2019 Dec 6. Immunol Invest. 2020. PMID: 31809611

8

On-target and direct modulation of alloreactive T cells by a nanoparticle carrying MHC alloantigen, regulatory molecules and CD47 in a murine model of alloskin transplantation.

Shahzad KA, Wan X, Zhang L, Pei W, Zhang A, Younis M, Wang W, Shen C. Shahzad KA, et al. Among authors: zhang l, zhang a. Drug Deliv. 2018 Nov;25(1):703-715. doi: 10.1080/10717544.2018.1447049. Drug Deliv. 2018. PMID: 29508634 Free PMC article.

9

Direct modulation of myelin-autoreactive CD4⁺ and CD8⁺ T cells in EAE mice by a tolerogenic nanoparticle co-carrying myelin peptide-loaded major histocompatibility complexes, CD47 and multiple regulatory molecules.

Pei W, Wan X, Shahzad KA, Zhang L, Song S, Jin X, Wang L, Zhao C, Shen C. Pei W, et al. Among authors: zhang l. Int J Nanomedicine. 2018 Jun 27;13:3731-3750. doi: 10.2147/IJN.S164500. eCollection 2018. Int J Nanomedicine. 2018. PMID: 29983566 Free PMC article.

10

A biodegradable killer microparticle to selectively deplete antigen-specific T cells in vitro and in vivo.

Wang W, Fang K, Li MC, Chang D, Shahzad KA, Xu T, Zhang L, Gu N, Shen CL. Wang W, et al. Among authors: zhang l. Oncotarget. 2016 Mar 15;7(11):12176-90. doi: 10.18632/oncotarget.7519. Oncotarget. 2016. PMID: 26910923 Free PMC article.

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