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Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.
Gauchotte G, Hergalant S, Vigouroux C, Casse JM, Houlgatte R, Kaoma T, Helle D, Brochin L, Rech F, Peyre M, Labrousse F, Vallar L, Guéant JL, Vignaud JM, Battaglia-Hsu SF. Gauchotte G, et al. Among authors: gueant jl. J Pathol. 2017 Aug;242(4):421-434. doi: 10.1002/path.4916. Epub 2017 Jul 5. J Pathol. 2017. PMID: 28493484
Vitamin B12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and up-regulates PP2A, proNGF, and TACE.
Battaglia-Hsu SF, Akchiche N, Noel N, Alberto JM, Jeannesson E, Orozco-Barrios CE, Martinez-Fong D, Daval JL, Guéant JL. Battaglia-Hsu SF, et al. Among authors: gueant jl. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21930-5. doi: 10.1073/pnas.0811794106. Epub 2009 Dec 3. Proc Natl Acad Sci U S A. 2009. PMID: 19959661 Free PMC article.
Methyl donor deficiency induces cardiomyopathy through altered methylation/acetylation of PGC-1α by PRMT1 and SIRT1.
Garcia MM, Guéant-Rodriguez RM, Pooya S, Brachet P, Alberto JM, Jeannesson E, Maskali F, Gueguen N, Marie PY, Lacolley P, Herrmann M, Juillière Y, Malthiery Y, Guéant JL. Garcia MM, et al. Among authors: gueant jl, gueant rodriguez rm. J Pathol. 2011 Nov;225(3):324-35. doi: 10.1002/path.2881. Epub 2011 Jun 1. J Pathol. 2011. PMID: 21633959
Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells.
Akchiche N, Bossenmeyer-Pourié C, Kerek R, Martin N, Pourié G, Koziel V, Helle D, Alberto JM, Ortiou S, Camadro JM, Léger T, Guéant JL, Daval JL. Akchiche N, et al. Among authors: gueant jl. FASEB J. 2012 Oct;26(10):3980-92. doi: 10.1096/fj.12-205757. Epub 2012 Jun 19. FASEB J. 2012. PMID: 22713523
467 results