Sagawa M - Search Results

1

HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications.

Harada T, Ohguchi H, Grondin Y, Kikuchi S, Sagawa M, Tai YT, Mazitschek R, Hideshima T, Anderson KC. Harada T, et al. Among authors: sagawa m. Leukemia. 2017 Dec;31(12):2670-2677. doi: 10.1038/leu.2017.144. Epub 2017 May 11. Leukemia. 2017. PMID: 28490812 Free PMC article.

2

KDM6B modulates MAPK pathway mediating multiple myeloma cell growth and survival.

Ohguchi H, Harada T, Sagawa M, Kikuchi S, Tai YT, Richardson PG, Hideshima T, Anderson KC. Ohguchi H, et al. Among authors: sagawa m. Leukemia. 2017 Dec;31(12):2661-2669. doi: 10.1038/leu.2017.141. Epub 2017 May 10. Leukemia. 2017. PMID: 28487543 Free PMC article.

3

Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma.

Sagawa M, Ohguchi H, Harada T, Samur MK, Tai YT, Munshi NC, Kizaki M, Hideshima T, Anderson KC. Sagawa M, et al. Clin Cancer Res. 2017 Sep 1;23(17):5225-5237. doi: 10.1158/1078-0432.CCR-17-0263. Epub 2017 Apr 25. Clin Cancer Res. 2017. PMID: 28442502 Free PMC article.

4

Combination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells.

Suzuki R, Kikuchi S, Harada T, Mimura N, Minami J, Ohguchi H, Yoshida Y, Sagawa M, Gorgun G, Cirstea D, Cottini F, Jakubikova J, Tai YT, Chauhan D, Richardson PG, Munshi N, Ando K, Utsugi T, Hideshima T, Anderson KC. Suzuki R, et al. Among authors: sagawa m. PLoS One. 2015 Dec 2;10(12):e0143847. doi: 10.1371/journal.pone.0143847. eCollection 2015. PLoS One. 2015. PMID: 26630652 Free PMC article.

5

The gold compound auranofin induces apoptosis of human multiple myeloma cells through both down-regulation of STAT3 and inhibition of NF-κB activity.

Nakaya A, Sagawa M, Muto A, Uchida H, Ikeda Y, Kizaki M. Nakaya A, et al. Among authors: sagawa m. Leuk Res. 2011 Feb;35(2):243-9. doi: 10.1016/j.leukres.2010.05.011. Epub 2010 Jun 12. Leuk Res. 2011. PMID: 20542334

6

Successful treatment with a modified bortezomib schedule of weekly and longer intervals for patients with refractory/resistance multiple myeloma.

Tokuhira M, Watanabe R, Nemoto T, Hanzawa K, Sagawa M, Tomikawa T, Mori S, Kizaki M. Tokuhira M, et al. Among authors: sagawa m. Leuk Res. 2011 May;35(5):591-7. doi: 10.1016/j.leukres.2010.11.013. Epub 2010 Dec 16. Leuk Res. 2011. PMID: 21167601 Clinical Trial.

7

Gossypol induces apoptosis in multiple myeloma cells by inhibition of interleukin-6 signaling and Bcl-2/Mcl-1 pathway.

Sadahira K, Sagawa M, Nakazato T, Uchida H, Ikeda Y, Okamoto S, Nakajima H, Kizaki M. Sadahira K, et al. Among authors: sagawa m. Int J Oncol. 2014 Dec;45(6):2278-86. doi: 10.3892/ijo.2014.2652. Epub 2014 Sep 15. Int J Oncol. 2014. PMID: 25231749 Free PMC article.

8

The role of TC-PTP (PTPN2) in modulating sensitivity to imatinib and interferon-α in CML cell line, KT-1 cells.

Nishiyama-Fujita Y, Shimizu T, Sagawa M, Uchida H, Kizaki M. Nishiyama-Fujita Y, et al. Among authors: sagawa m. Leuk Res. 2013 Sep;37(9):1150-5. doi: 10.1016/j.leukres.2013.05.008. Epub 2013 Jun 4. Leuk Res. 2013. PMID: 23759247

9

NK4, an antagonist of hepatocyte growth factor (HGF), inhibits growth of multiple myeloma cells: molecular targeting of angiogenic growth factor.

Du W, Hattori Y, Yamada T, Matsumoto K, Nakamura T, Sagawa M, Otsuki T, Niikura T, Nukiwa T, Ikeda Y. Du W, et al. Among authors: sagawa m. Blood. 2007 Apr 1;109(7):3042-9. doi: 10.1182/blood-2006-02-003103. Blood. 2007. PMID: 17179234 Free article.

10

Structure-activity relationships of benzhydrol derivatives based on 1'-acetoxychavicol acetate (ACA) and their inhibitory activities on multiple myeloma cell growth via inactivation of the NF-κB pathway.

Misawa T, Dodo K, Ishikawa M, Hashimoto Y, Sagawa M, Kizaki M, Aoyama H. Misawa T, et al. Among authors: sagawa m. Bioorg Med Chem. 2015 May 1;23(9):2241-6. doi: 10.1016/j.bmc.2015.02.039. Epub 2015 Mar 7. Bioorg Med Chem. 2015. PMID: 25801158

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