Ayrault O - Search Results

1

ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas.

Grausam KB, Dooyema SDR, Bihannic L, Premathilake H, Morrissy AS, Forget A, Schaefer AM, Gundelach JH, Macura S, Maher DM, Wang X, Heglin AH, Ge X, Zeng E, Puget S, Chandrasekar I, Surendran K, Bram RJ, Schüller U, Talyor MD, Ayrault O, Zhao H. Grausam KB, et al. Among authors: ayrault o. Cancer Res. 2017 Jul 15;77(14):3766-3777. doi: 10.1158/0008-5472.CAN-16-1836. Epub 2017 May 10. Cancer Res. 2017. PMID: 28490517 Free PMC article.

2

Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors.

Zindy F, Uziel T, Ayrault O, Calabrese C, Valentine M, Rehg JE, Gilbertson RJ, Sherr CJ, Roussel MF. Zindy F, et al. Among authors: ayrault o. Cancer Res. 2007 Mar 15;67(6):2676-84. doi: 10.1158/0008-5472.CAN-06-3418. Cancer Res. 2007. PMID: 17363588

3

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development.

Zhao H, Ayrault O, Zindy F, Kim JH, Roussel MF. Zhao H, et al. Among authors: ayrault o. Genes Dev. 2008 Mar 15;22(6):722-7. doi: 10.1101/gad.1636408. Genes Dev. 2008. PMID: 18347090 Free PMC article.

4

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.

Ayrault O, Zhao H, Zindy F, Qu C, Sherr CJ, Roussel MF. Ayrault O, et al. Cancer Res. 2010 Jul 1;70(13):5618-27. doi: 10.1158/0008-5472.CAN-09-3740. Epub 2010 Jun 1. Cancer Res. 2010. PMID: 20516124 Free PMC article.

5

Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins.

Boulay G, Dubuissez M, Van Rechem C, Forget A, Helin K, Ayrault O, Leprince D. Boulay G, et al. Among authors: ayrault o. J Biol Chem. 2012 Mar 23;287(13):10509-10524. doi: 10.1074/jbc.M111.320234. Epub 2012 Feb 7. J Biol Chem. 2012. PMID: 22315224 Free PMC article.

6

Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression.

Murphy BL, Obad S, Bihannic L, Ayrault O, Zindy F, Kauppinen S, Roussel MF. Murphy BL, et al. Among authors: ayrault o. Cancer Res. 2013 Dec 1;73(23):7068-78. doi: 10.1158/0008-5472.CAN-13-0927. Epub 2013 Oct 21. Cancer Res. 2013. PMID: 24145352 Free PMC article.

7

Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.

Morfouace M, Shelat A, Jacus M, Freeman BB 3rd, Turner D, Robinson S, Zindy F, Wang YD, Finkelstein D, Ayrault O, Bihannic L, Puget S, Li XN, Olson JM, Robinson GW, Guy RK, Stewart CF, Gajjar A, Roussel MF. Morfouace M, et al. Among authors: ayrault o. Cancer Cell. 2014 Apr 14;25(4):516-29. doi: 10.1016/j.ccr.2014.02.009. Epub 2014 Mar 27. Cancer Cell. 2014. PMID: 24684846 Free PMC article.

8

Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors.

Forget A, Bihannic L, Cigna SM, Lefevre C, Remke M, Barnat M, Dodier S, Shirvani H, Mercier A, Mensah A, Garcia M, Humbert S, Taylor MD, Lasorella A, Ayrault O. Forget A, et al. Among authors: ayrault o. Dev Cell. 2014 Jun 23;29(6):649-61. doi: 10.1016/j.devcel.2014.05.014. Dev Cell. 2014. PMID: 24960692 Free article.

9

MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.

Hoch L, Faure H, Roudaut H, Schoenfelder A, Mann A, Girard N, Bihannic L, Ayrault O, Petricci E, Taddei M, Rognan D, Ruat M. Hoch L, et al. Among authors: ayrault o. FASEB J. 2015 May;29(5):1817-29. doi: 10.1096/fj.14-267849. Epub 2015 Jan 30. FASEB J. 2015. PMID: 25636740 Free PMC article.

10

Insights into cerebellar development and medulloblastoma.

Bihannic L, Ayrault O. Bihannic L, et al. Among authors: ayrault o. Bull Cancer. 2016 Jan;103(1):30-40. doi: 10.1016/j.bulcan.2015.11.002. Epub 2015 Dec 11. Bull Cancer. 2016. PMID: 26688373 Review.

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