Liu Y - Search Results

1

An Overview on Screening Methods for Lysine Specific Demethylase 1 (LSD1) Inhibitors.

Zheng YC, Chang J, Zhang T, Suo FZ, Chen XB, Liu Y, Zhao B, Yu B, Liu HM. Zheng YC, et al. Among authors: liu y, liu hm. Curr Med Chem. 2017;24(23):2496-2504. doi: 10.2174/0929867324666170509114321. Curr Med Chem. 2017. PMID: 28486922 Review.

2

Design, synthesis and biological evaluation of [1,2,4]triazolo[1,5-a]pyrimidines as potent lysine specific demethylase 1 (LSD1/KDM1A) inhibitors.

Wang S, Zhao LJ, Zheng YC, Shen DD, Miao EF, Qiao XP, Zhao LJ, Liu Y, Huang R, Yu B, Liu HM. Wang S, et al. Among authors: liu y, liu hm. Eur J Med Chem. 2017 Jan 5;125:940-951. doi: 10.1016/j.ejmech.2016.10.021. Epub 2016 Oct 14. Eur J Med Chem. 2017. PMID: 27769034

3

Baicalin, a natural LSD1 inhibitor.

Zheng YC, Shen DD, Ren M, Liu XQ, Wang ZR, Liu Y, Zhang QN, Zhao LJ, Zhao LJ, Ma JL, Yu B, Liu HM. Zheng YC, et al. Among authors: liu y, liu hm, liu xq. Bioorg Chem. 2016 Dec;69:129-131. doi: 10.1016/j.bioorg.2016.10.004. Epub 2016 Oct 11. Bioorg Chem. 2016. PMID: 27814566

4

LPE-1, an orally active pyrimidine derivative, inhibits growth and mobility of human esophageal cancers by targeting LSD1.

Wang B, Zhao B, Pang LP, Zhao YD, Guo Q, Wang JW, Zheng YC, Zhang XH, Liu Y, Liu GY, Guo WG, Wang C, Li ZH, Mao XJ, Yu B, Ma LY, Liu HM. Wang B, et al. Among authors: liu y, liu gy, liu hm. Pharmacol Res. 2017 Aug;122:66-77. doi: 10.1016/j.phrs.2017.05.025. Epub 2017 May 30. Pharmacol Res. 2017. PMID: 28571892

5

Design, synthesis and preliminary antiproliferative activity studies of new diheteroaryl thioether derivatives.

Li ZH, Liu XQ, Zhao TQ, Geng PF, Liu Y, Zhao B, Guo WG, Yu B, Liu HM. Li ZH, et al. Among authors: liu y, liu hm, liu xq. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4377-4382. doi: 10.1016/j.bmcl.2017.08.021. Epub 2017 Aug 18. Bioorg Med Chem Lett. 2017. PMID: 28838695

6

Exploration of 1,2,3-triazole-pyrimidine hybrids as potent reversal agents against ABCB1-mediated multidrug resistance.

Wang B, Zhao B, Chen ZS, Pang LP, Zhao YD, Guo Q, Zhang XH, Liu Y, Liu GY, Hao-Zhang, Zhang XY, Ma LY, Liu HM. Wang B, et al. Among authors: liu y, liu gy, liu hm. Eur J Med Chem. 2018 Jan 1;143:1535-1542. doi: 10.1016/j.ejmech.2017.10.041. Epub 2017 Oct 21. Eur J Med Chem. 2018. PMID: 29126726

7

Discovery of 5-Cyano-6-phenylpyrimidin Derivatives Containing an Acylurea Moiety as Orally Bioavailable Reversal Agents against P-Glycoprotein-Mediated Mutidrug Resistance.

Wang B, Ma LY, Wang JQ, Lei ZN, Gupta P, Zhao YD, Li ZH, Liu Y, Zhang XH, Li YN, Zhao B, Chen ZS, Liu HM. Wang B, et al. Among authors: liu y, liu hm. J Med Chem. 2018 Jul 26;61(14):5988-6001. doi: 10.1021/acs.jmedchem.8b00335. Epub 2018 Jul 18. J Med Chem. 2018. PMID: 29975529

8

Design, synthesis and biological mechanisms research on 1,2,3-triazole derivatives of Jiyuan Oridonin A.

Ke Y, Wang W, Zhao LF, Liang JJ, Liu Y, Zhang X, Feng K, Liu HM. Ke Y, et al. Among authors: liu y, liu hm. Bioorg Med Chem. 2018 Sep 15;26(17):4761-4773. doi: 10.1016/j.bmc.2017.11.005. Epub 2017 Nov 4. Bioorg Med Chem. 2018. PMID: 30143365

9

Jesridonin in combination with paclitaxel demonstrates synergistic anti-tumor activity in human esophageal carcinoma cells.

Wang C, Yang D, Jiang L, Wang S, Wang J, Zhou K, Shi X, Chang L, Liu Y, Ke Y, Liu H. Wang C, et al. Among authors: liu y, liu h. Bioorg Med Chem Lett. 2017 May 1;27(9):2058-2062. doi: 10.1016/j.bmcl.2017.02.008. Epub 2017 Feb 7. Bioorg Med Chem Lett. 2017. PMID: 28285918

10

Thiosemicarbazone-based selective proliferation inactivators inhibit gastric cancer cell growth, invasion, and migration.

Hu B, Wang B, Zhao B, Guo Q, Li ZH, Zhang XH, Liu GY, Liu Y, Tang Y, Luo F, Du Y, Chen YX, Ma LY, Liu HM. Hu B, et al. Among authors: liu gy, liu y, liu hm. Medchemcomm. 2017 Oct 23;8(12):2173-2180. doi: 10.1039/c7md00353f. eCollection 2017 Dec 1. Medchemcomm. 2017. PMID: 30108734 Free PMC article.

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